Evidence map›Paper›PMID 20887642›Full record

ReviewGenome biology2010

Rat traps: filling the toolbox for manipulating the rat genome.

Ruben van Boxtel, Edwin Cuppen

Open access · goldAbstract readReview
In one paragraph

Review in Genome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The case for genetic monitoring of mice and rats used in biomedical research.Mammalian genome : official journal of the International Mammalian Genome Society · 2013
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ruben van BoxtelHubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Royal Netherlands Academy of Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
Edwin Cuppen
Cancer Genomics Centre · NLHubrecht Institute for Developmental Biology and Stem Cell Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.

Indexed as

GenomeAnimalsChromosome MappingGene TargetingGenetic Predisposition to DiseaseGenetic TechniquesModels, AnimalModels, GeneticMutagenesisPhenotypePluripotent Stem CellsRats

Identifiers

PMID20887642
PMCPMC2965381
OpenAlexW2112188586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.