ArticleHuman mutation2010
Evaluating self-declared ancestry of U.S. Americans with autosomal, Y-chromosomal and mitochondrial DNA.
Article in Human mutation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 94 citations in OpenAlex.
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- Forensic biogeographical ancestry inference: recent insights and current trends.Genes & genomics · 2023Review
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- A SNP panel for early detection of artificial chimerism in HSCT patients using TaqMan technology.International journal of legal medicine · 2020Article
- Next generation sequencing of a set of ancestry-informative SNPs: ancestry assignment of three continental populations and estimating ancestry composition for Mongolians.Molecular genetics and genomics : MGG · 2020Article
- Twenty-seven continental ancestry-informative SNP analysis of bone remains to resolve a forensic case.Forensic sciences research · 2019Article
- A Screening Test forFrontiers in pharmacology · 2019Article
- Human ancestry indentification under resource constraints -- what can one chromosome tell us about human biogeographical ancestry?BMC medical genomics · 2018Article
- Prediction of biogeographical ancestry from genotype: a comparison of classifiers.International journal of legal medicine · 2017Article
- A panel of 130 autosomal single-nucleotide polymorphisms for ancestry assignment in five Asian populations and in Caucasians.Forensic science, medicine, and pathology · 2017Article
- Long-distance dispersal suppresses introgression of local alleles during range expansions.Heredity · 2017Article
- Potential forensic use of a 33 X-InDel panel in the Argentinean population.International journal of legal medicine · 2017Review
- Exploration of SNP variants affecting hair colour prediction in Europeans.International journal of legal medicine · 2015Article
- Association between Y haplogroups and autosomal AIMs reveals intra-population substructure in Bolivian populations.International journal of legal medicine · 2015Article
- The genetic ancestry of African Americans, Latinos, and European Americans across the United States.American journal of human genetics · 2015Article
- Extensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in Africa.Evolutionary bioinformatics online · 2015Article
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- Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa.Gene regulation and systems biology · 2014Article
- Biological races in humans.Studies in history and philosophy of biological and biomedical sciences · 2013Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current U.S. population represents an amalgam of individuals originating mainly from four continental regions (Africa, Europe, Asia and America). To study the genetic ancestry and compare with self-declared ancestry we have analyzed paternally, maternally and bi-parentally inherited DNA markers sensitive for indicating continental genetic ancestry in all four major U.S. American groups. We found that self-declared U.S. Hispanics and U.S. African Americans tend to show variable degrees of continental genetic admixture among the three genetic systems, with evidence for a marked sex-biased admixture history. Moreover, for these two groups we observed significant regional variation across the country in genetic admixture. In contrast, self-declared U.S. European and U.S. Asian Americans were genetically more homogeneous at the continental ancestry level. Two autosomal ancestry-sensitive markers located in skin pigmentation candidate genes showed significant differences in self-declared U.S. African Americans or U.S. European Americans, relative to their assumed parental populations from Africa or Europe. This provides genetic support for the importance of skin color in the complex process of ancestry identification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.