Evidence map›Paper›PMID 20886310›Full record

Trial reportNeurocritical care2011

Treatment of resistant fever: new method of local cerebral cooling.

Susanne Mink, Urs Schwarz, Regina Mudra, Christoph Gugl, Jürg Fröhlich, Emanuela Keller

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Neurocritical care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Therapeutic hypothermia for acute neurological injuries.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susanne MinkDepartment of Neurosurgery, Neuroscience Intensive Care Unit, University Hospital of Zurich, Zurich, Switzerland. smink@partners.org
Urs Schwarz
Regina Mudra
Christoph Gugl
Jürg Fröhlich
Emanuela Keller

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFever in neurocritical care patients is common and has a negative impact on neurological outcome. The purpose of this prospective observational study was (1) to evaluate the practicability of cooling with newly developed neck pads in the daily setting of neurointensive care unit (NICU) patients and (2) to evaluate its effectiveness as a surrogate endpoint to indicate the feasibility of neck cooling as a new method for intractable fever.

methodsNine patients with ten episodes of intractable fever and aneurysmal subarachnoid hemorrhage were treated with one of two different shapes of specifically adapted cooling neck pads. Temperature values of the brain, blood, and urinary bladder were taken close meshed after application of the cooling neck pads up to hour 8.

resultsThe brain, blood, and urinary bladder temperatures decreased significantly from hour 0 to a minimum in hour 5 (P < 0.01). After hour 5, instead of continuous cooling in all the patients, the temperature of all the three sites remounted.

conclusionThis study showed the practicability of local cooling for intractable fever using the newly developed neck pads in the daily setting of NICU patients.

Indexed as

Critical CareAdultEquipment DesignFemaleFeverHumansHypothermia, InducedMaleMiddle AgedProspective StudiesSubarachnoid HemorrhageTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.