Evidence map›Paper›PMID 20886057›Full record

ArticleInternational journal of Alzheimer's disease2010

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases.

Philipp Spitzer, Hans Wolfgang Klafki, Kaj Blennow, Luc Buée, Hermann Esselmann, Sanna-Kaisa Herruka, Connie Jimenez, Peter Klivenyi, Piotr Lewczuk, Juan Manuel Maler and 12 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of Alzheimer's disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Neurochemical biomarkers in Alzheimer's disease and related disorders.Therapeutic advances in neurological disorders · 2012
    Article
  8. Article
  9. Article
  10. Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia.International journal of Alzheimer's disease · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 7 countries.

Philipp SpitzerLaboratory for Molecular Neurobiology, Department of Psychiatry and Psychotherapy, University of Duisburg-Essen, LVR-Klinikum Essen, Virchowstraße 174, 45147 Essen, Germany.
Hans Wolfgang Klafki
Kaj Blennow
Luc Buée
Hermann Esselmann
Sanna-Kaisa Herruka
Connie Jimenez
Peter Klivenyi
Piotr Lewczuk
Juan Manuel Maler
Katrin Markus
Helmut E Meyer
Chris Morris
Thorsten Müller
Markus Otto
Lucilla Parnetti
Hilkka Soininen
Susanna Schraen
Charlotte Teunissen
Laszlo Vecsei
Henrik Zetterberg
Jens Wiltfang
University of Duisburg-Essen · DERuhr University Bochum · DEAmsterdam UMC Location VUmc · NLFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversité Lille Nord de France · FRUniversity of Eastern Finland · FIUniversity of Gothenburg · SEUniversity of Szeged · HUAzienda Ospedaliera di Perugia · ITUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"clinical NEUroPROteomics of neurodegenerative diseases" (cNEUPRO) is a Specific Targeted Research Project (STREP) within the sixth framework program of the European Commission dedicated to the search for novel biomarker candidates for Alzheimer's disease and other neurodegenerative diseases. The ultimate goal of cNEUPRO is to identify one or more valid biomarker(s) in blood and CSF applicable to support the early and differential diagnosis of dementia disorders. The consortium covers all steps required for the discovery of novel biomarker candidates such as acquisition of high quality CSF and blood samples from relevant patient groups and controls, analysis of body fluids by various methods, and finally assay development and assay validation. Here we report the standardized procedures for diagnosis and preanalytical sample-handling within the project, as well as the status of the ongoing research activities and some first results.

Identifiers

PMID20886057
PMCPMC2945639
OpenAlexW2134671793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.