ArticleJournal of applied physiology (Bethesda, Md. : 1985)2010
Combined heat and mental stress alters neurovascular control in humans.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies.Nature communications · 2025Pooled it
- Calculating Load and Intensity Using Muscle Oxygen Saturation Data.Sports (Basel, Switzerland) · 2024Article
- Influence of Heat Exposure on Motor Control Performance and Learning as Well as Physiological Responses to Visuomotor Accuracy Tracking Task.International journal of environmental research and public health · 2022Article
- Moderate whole body heating attenuates the exercise pressor reflex responses in older humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Background factors of chemical intolerance and parent-child relationships.Environmental health and preventive medicine · 2018Article
- Muscle sympathetic nerve activity response to heat stress is attenuated in chronic heart failure patients.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Sympathetic neural reactivity to mental stress in offspring of hypertensive parents: 20 years revisited.American journal of physiology. Heart and circulatory physiology · 2016Article
- Sympathoneural and adrenomedullary responses to mental stress.Comprehensive Physiology · 2015Review
- Characteristics of sensitization associated with chronic pain conditions.The Clinical journal of pain · 2014Article
- Forearm vascular responses to mental stress in healthy older adults.Physiological reports · 2013Article
- Mental Stress Elicits Sustained and Reproducible Increases in Skin Sympathetic Nerve Activity.Physiological reports · 2013Article
- A mechanism-based approach to prevention of and therapy for fibromyalgia.Pain research and treatment · 2012Article
- Negligible heat strain in armored vehicle officers wearing personal body armor.Journal of occupational medicine and toxicology (London, England) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
This study examined the effect of combined heat and mental stress on neurovascular control. We hypothesized that muscle sympathetic nerve activity (MSNA) and forearm vascular responses to mental stress would be augmented during heat stress. Thirteen subjects performed 5 min of mental stress during normothermia (Tcore; 37 ± 0°C) and heat stress (38 ± 0°C). Heart rate, mean arterial pressure (MAP), MSNA, forearm vascular conductance (FVC; venous occlusion plethysmography), and forearm skin vascular conductance (SkVCf; via laser-Doppler) were analyzed. Heat stress increased heart rate, MSNA, SkVCf, and FVC at rest but did not change MAP. Mental stress increased MSNA and MAP during both thermal conditions; however, the increase in MAP during heat stress was blunted, whereas the increase in MSNA was accentuated, compared with normothermia (time × condition; P < 0.05 for both). Mental stress decreased SkVCf during heat stress but not during normothermia (time × condition, P < 0.01). Mental stress elicited similar increases in heart rate and FVC during both conditions. In one subject combined heat and mental stress induced presyncope coupled with atypical blood pressure and cutaneous vascular responses. In conclusion, these findings indicate that mental stress elicits a blunted increase of MAP during heat stress, despite greater increases in total MSNA and cutaneous vasoconstriction. The neurovascular responses to combined heat and mental stress may be clinically relevant to individuals frequently exposed to mentally demanding tasks in hyperthermic environmental conditions (i.e., soldiers, firefighters, and athletes).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.