Trial reportBMJ (Clinical research ed.)2010
The effect of a multifaceted empowerment strategy on decision making about the number of embryos transferred in in vitro fertilisation: randomised controlled trial.
Trial report in BMJ (Clinical research ed.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00315029 (Patient-Centered Implementation of Elective Single Embryo Transfer), which is not on this map. Cited by 32 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Patient-Centered Implementation of Elective Single Embryo Transfer (eSET) in in Vitro Fertilisation (IVF) and Intracytoplasmic Sperm Injection (ICSI)
Who cites it
32 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Decision coaching for people making healthcare decisions.The Cochrane database of systematic reviews · 2021Pooled it
- Pooled it
- Pooled it
- Interventions for increasing the use of shared decision making by healthcare professionals.The Cochrane database of systematic reviews · 2018Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017Pooled it
- Undetermined impact of patient decision support interventions on healthcare costs and savings: systematic review.BMJ (Clinical research ed.) · 2014Pooled it
- Providing information about options in patient decision aids.BMC medical informatics and decision making · 2013Pooled it
- Addressing health literacy in patient decision aids.BMC medical informatics and decision making · 2013Pooled it
- Effectiveness of birth plan counselling based on shared decision making: A cluster randomized controlled trial (APLANT).PloS one · 2022Trial
- Development and pilot evaluation of a personalized decision support intervention for low risk prostate cancer patients.Cancer medicine · 2020Trial
- Evaluating the Use of a Decision Aid for Parents Facing Extremely Premature Delivery: A Randomized Trial.The Journal of pediatrics · 2019Trial
- Trial
- Trial
- Cost effectiveness of a web-based decision aid for parents deciding about MMR vaccination: a three-arm cluster randomised controlled trial in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014Trial
- Implementation strategies of internet-based asthma self-management support in usual care. Study protocol for the IMPASSE cluster randomized trial.Implementation science : IS · 2012Trial
- A Bayesian reevaluation of randomized controlled trials in assisted reproductive technology: quantifying evidence strength for null and alternative hypotheses.Frontiers in endocrinology · 2026Article
- Evaluation of a patient decision aid for opportunistic salpingectomy and salpingectomy as sterilization method to prevent ovarian cancer.Acta obstetricia et gynecologica Scandinavica · 2025Observational
- Are shared decision making studies well enough described to be replicated? Secondary analysis of a Cochrane systematic review.PloS one · 2022Article
- Co-Design of a Disease Activity Based Self-Management Approach for Patients with Rheumatoid Arthritis.Mediterranean journal of rheumatology · 2021Article
Corrections and comments
- Commented on by
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effects of a multifaceted empowerment strategy on the actual use of single embryo transfer after in vitro fertilisation.
designRandomised controlled trial.
settingFive in vitro fertilisation clinics in the Netherlands.
participants308 couples (women aged <40) on the waiting list for a first in vitro fertilisation cycle.
interventionsThe multifaceted strategy aimed to empower couples in deciding how many embryos should be transferred. The strategy consisted of a decision aid, support of a nurse specialising in in vitro fertilisation, and the offer of reimbursement by way of an extra treatment cycle. The control group received standard care for in vitro fertilisation.
main outcome measuresUse of single embryo transfer in the first and second treatment cycles as well as decision making variables and costs of the empowerment strategy.
resultsAfter the first treatment cycle, single embryo transfer was used by 43% (65/152) of couples in the intervention group and 32% (50/156) in the control group (difference 11%, 95% confidence interval 0% to 22%; P=0.05). After the second treatment cycle, single embryo transfer was used by 26% (14/154) of couples in the intervention group compared with 16% (8/51) in the control group (difference 10%, -6% to 26%; P=0.20). Compared with couples receiving standard care, those receiving the empowerment strategy had significantly higher empowerment and knowledge levels but no differences in anxiety levels. Mean total savings per couple in the intervention group were calculated to be €169.75 (£146.77; $219.12).
conclusionsA multifaceted empowerment strategy encouraged use of single embryo transfer, increased patients' knowledge, reduced costs, and had no effect on levels of anxiety or depression. This strategy could therefore be an important tool to reduce the twin pregnancy rate after in vitro fertilisation. This trial did not, however, demonstrate the anticipated 25% difference in use of single embryo transfer of the power calculation.
trial registrationClinicalTrials.gov NCT00315029.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.