Evidence map›Paper›PMID 20884193›Full record

ReviewCurrent opinion in immunology2010

Mast cell mediators in tolerance.

Victor C de Vries, Randolph J Noelle

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. The mast cell: A Janus in kidney transplants.Frontiers in immunology · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Mast Cell Biology at Molecular Level: a Comprehensive Review.Clinical reviews in allergy & immunology · 2020
    Review
  10. Analysis of Mrgprb2 Receptor-Evoked CaFrontiers in immunology · 2020
    Article
  11. Carcinogenesis: the cancer cell-mast cell connection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Mast cell function: a new vision of an old cell.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2014
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Victor C de VriesDepartment of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH, USA.
Randolph J Noelle

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
TNF FAMILY MEMBERS GOVERN CD4 AND CD8 RESPONSES IN GVHDR01AI048667 · NIAID · DARTMOUTH COLLEGE · PI NOELLE, RANDOLPH J. · 2001 to 2010
$3.8M
Medical Research Council G0802651NCI NIH HHS P30 CA023108NIAID NIH HHS AI048667NIAID NIH HHS R01 AI048667
6 · The paper itself

Abstract

Our knowledge on the function of mast cells (MC) as part of the immune system has expanded from 'key cells in mediating allergy' to 'tunable regulators of the immune response'. Over the past years however, a large body of evidence has been presented indicating a more regulatory role for MC in the immune system by both contact dependent and independent mechanisms. Considering the vast amount of soluble mediators released by MC, it is not surprising that some are involved in the maintenance of peripheral tolerance and the control or even help to resolve ongoing inflammation. In this review we will focus on the immunosuppressive function of some of these mediators produced by MC in a wide variety of disease models.

Indexed as

AnimalsCytokinesHumansImmune ToleranceMast CellsCytokines

Identifiers

PMID20884193
PMCPMC3809014

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.