ArticleThe Journal of pediatrics2011
Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth cohort.
Article in The Journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Early age of dog exposure is negatively associated with atopic dermatitis: A comprehensive analysis.Pediatric research · 2025Pooled it
- Identification of two early life eczema and non-eczema phenotypes with high risk for asthma development.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Trial
- Breastfeeding, Family Stress, and Climate as Key Determinants of Atopic Dermatitis Severity in Children: A Cross-Sectional Study.Clinical, cosmetic and investigational dermatology · 2026Article
- The association between the composition of the early-life intestinal microbiome and eczema in the first year of life.Frontiers in microbiomes · 2023Article
- Article
- Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021Article
- Early Life Domestic Pet Ownership, and the Risk of Pet Sensitization and Atopic Dermatitis in Preschool Children: A Prospective Birth Cohort in Shanghai.Frontiers in pediatrics · 2020Article
- Evaluation of eczema, asthma, allergic rhinitis and allergies among the Grade-1 children of Iqaluit.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018Article
- Article
- Subgroup differences in the associations between dog exposure during the first year of life and early life allergic outcomes.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2017Article
- The feline skin microbiota: The bacteria inhabiting the skin of healthy and allergic cats.PloS one · 2017Article
- Asking About Pets Enhances Patient Communication and Care: A Pilot Study.Inquiry : a journal of medical care organization, provision and financing · 2017Article
- Allergic Diseases and Internalizing Behaviors in Early Childhood.Pediatrics · 2016Article
- Atopic dermatitis is a serious health problem in Poland. Epidemiology studies based on the ECAP study.Postepy dermatologii i alergologii · 2015Article
- The role of the early-life environment in the development of allergic disease.Immunology and allergy clinics of North America · 2015Review
- Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis.Journal of the American Academy of Dermatology · 2014Review
- [Which was first: the chicken or the egg? : an update on sensitization risks and pathways: is sensitization secondary to eczema or vice-versa?].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2012Article
- Exposure to cats: update on risks for sensitization and allergic diseases.Current allergy and asthma reports · 2012Review
- Infant origins of childhood asthma associated with specific molds.The Journal of allergy and clinical immunology · 2012Article
- Diesel exhaust exposure, wheezing and sneezing.Allergy, asthma & immunology research · 2012Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo examine risk factors for eczema at age 4 years. STUDY
designBeginning at 1 year of age, infants of atopic parents (n = 636) had annual clinical evaluations and skin prick tests (SPTs) to 15 aeroallergens and milk and egg. Parents completed validated surveys on eczema and environmental exposures. House dust samples were evaluated for allergens and endotoxin. Eczema was defined as a parental report of scratching, and redness, "raised bumps," or dry skin/scaling for 6 of the last 12 months.
resultsAt age 4 years, a total of 90 children (14%) had eczema. Not having a dog before 1 year of age and being dog SPT+ at 1, 2, or 3 years of age conferred a 4-fold higher risk for eczema at age 4 years (adjusted odds ratio [aOR] = 3.9 [1.6-9.2]; P = .002). Among dog owners, however, dog SPT+ was not associated with significantly increased risk (aOR 1.3 [0.3-6.8]; P = .8). Among children with cats before 1 year of age, cat SPT+ conferred significantly increased risk for eczema (aOR = 13.3 [3.1-57.9]; P < .001). Among non-cat owners, cat SPT+ was not associated with increased risk (aOR = 1.1 [0.5-2.7]; P = .8).
conclusionDog ownership significantly reduced the risk for eczema at age 4 years among dog-sensitized children, cat ownership combined with cat sensitization significantly increased the risk.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.