ReviewJournal of clinical hypertension (Greenwich, Conn.)2010
Current evidence on the hemodynamic and blood pressure effects of isometric exercise in normotensive and hypertensive persons.
Review in Journal of clinical hypertension (Greenwich, Conn.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pivotal Study To Evaluate The Effectiveness of Isometric Handgrip Therapy In Prehypertensive And Hypertensive Patients
A Multicenter Randomized Controlled Trial of Exercise in Aortic Dissection Survivors
Who cites it
16 citing papers in PubMed.
- Time course of cardiovascular responses to acute sustained handgrip exercise in young physically active men.Physiological reports · 2025Article
- Effects of the intensity, duration and muscle mass factors of isometric exercise on acute local muscle hemodynamic responses and systematic blood pressure regulation.Frontiers in bioengineering and biotechnology · 2024Article
- Proinflammatory and Anti-inflammatory Cytokine Response to Isometric Handgrip Exercise and the Effects of Duration and Intensity of the Isometric Efforts in Prehypertensive Participants.Journal of chiropractic medicine · 2022Article
- Immune system response to isometric handgrip exercise and effects of duration and intensity of the exercise protocol on selected immune system parameters in prehypertensives.International journal of physiology, pathophysiology and pharmacology · 2022Article
- Safety of exercise for adults with thoracic aortic aneurysms and dissections.Frontiers in sports and active living · 2022Article
- Isometric Handgrip Exercise Training Improves Spirometric Parameters and Pulmonary Capacity.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Article
- The possibility that long-term isometric handgrip exercise contributes to left atrial enlargement in patients with hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Diving with hypertension and antihypertensive drugs.Diving and hyperbaric medicine · 2020Review
- Are Blood Pressure and Cardiovascular Stress Greater in Isometric or in Dynamic Resistance Exercise?Sports (Basel, Switzerland) · 2020Review
- Effects of Full Body Exergaming in Virtual Reality on Cardiovascular and Muscular Parameters: Cross-Sectional Experiment.JMIR serious games · 2019Article
- Abnormal sympathetic functioning is linked to familial hypertension in nonathletic young males.Journal of education and health promotion · 2019Article
- The safety of isometric exercise: Rethinking the exercise prescription paradigm for those with stage 1 hypertension.Medicine · 2018Article
- Evidence for exercise training in the management of hypertension in adults.Canadian family physician Medecin de famille canadien · 2015Review
- Metabolic syndrome and hypertension: regular exercise as part of lifestyle management.Current hypertension reports · 2014Review
- Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions.Sports medicine (Auckland, N.Z.) · 2014Review
- Exercise training improves hemodynamic recovery to isometric exercise in obese men with type 2 diabetes but not in obese women.Metabolism: clinical and experimental · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isometric exercise is associated with acute hemodynamic changes consisting of increases in systolic, diastolic, and mean arterial pressure and also an increase in heart rate and cardiac output. The peripheral vascular resistance is either not changed or decreased. These hemodynamic changes return to baseline values soon after the completion of exercise. Since isometric exercise is not an aerobic exercise, it was not recommended to hypertensive patients by national and international committee guidelines. Recent studies and meta-analyses of the subject have demonstrated, however, that isometric or resistance exercise does not raise resting blood pressure and frequently leads to a small decrease, which could be enhanced with the concomitant administration of antihypertensive drugs. Besides blood pressure, isometric exercise is associated with other beneficial effects consisting of an increase in muscle bulk, upper and lower body strength, increase in bone density, and a decrease in bone fractures. These changes are extremely beneficial to older patients by making them more mobile and increasing their quality of life. Based on these changes, the authors believe that isometric exercise, whether alone or in combination with dynamic exercise, should be recommended to hypertensive patients and be part of a comprehensive treatment regimen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.