Trial reportAlternative therapies in health and medicine
Mindfulness-based stress reduction for solid organ transplant recipients: a randomized controlled trial.
Trial report in Alternative therapies in health and medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 49 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
REDEFINE AYAO: Reducing Emotional Distress, Enhancing Function and Improving Network Engagement in Adolescent and Young Adult Oncology
Reducing the Effects of Active Surveillance Stress, Uncertainty and Rumination Thru Engagement in Mindfulness Education
Contribution of Learning and Practice of Different Complementary Therapies in Pulmonary Transplant Patients
Who cites it
49 citing papers in PubMed, 11 syntheses or guidelines pooled it, 138 citations in OpenAlex.
- Do psycho-behavioural interventions improve mental and physical health in chronic kidney disease? A systematic review of randomised controlled trials.Journal of nephrology · 2025Pooled it
- A systematic review of the effectiveness of psychological interventions in organ transplantation.Frontiers in psychology · 2025Pooled it
- Effects of mindfulness-based stress reduction on adults with sleep disturbance: an updated systematic review and meta-analysis.BMJ open · 2022Pooled it
- Self-reported poor quality of sleep in solid organ transplant: A systematic review.Transplantation reviews (Orlando, Fla.) · 2021Pooled it
- Psychological and Psychopathological Aspects of Kidney Transplantation: A Systematic Review.Frontiers in psychiatry · 2020Pooled it
- Differential sensitivity of mindfulness questionnaires to change with treatment: A systematic review and meta-analysis.Psychological assessment · 2019Pooled it
- The effect of mindfulness meditation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.Annals of the New York Academy of Sciences · 2019Pooled it
- Mindfulness training for psychological stress in family caregivers of persons with dementia: a systematic review and meta-analysis of randomized controlled trials.Clinical interventions in aging · 2017Pooled it
- Meditation programs for psychological stress and well-being: a systematic review and meta-analysis.JAMA internal medicine · 2014Pooled it
- Mindfulness: a systematic review of instruments to measure an emergent patient-reported outcome (PRO).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013Pooled it
- Meditative therapies for reducing anxiety: a systematic review and meta-analysis of randomized controlled trials.Depression and anxiety · 2012Pooled it
- Symptom reduction in kidney transplant patients from 20-minute mindful breathing: a randomized controlled trial.BMC nephrology · 2025Trial
- Telephone-adapted Mindfulness-based Stress Reduction (tMBSR) for patients awaiting kidney transplantation.Contemporary clinical trials · 2017Trial
- Telephone-adapted mindfulness-based stress reduction (tMBSR) for patients awaiting kidney transplantation: Trial design, rationale and feasibility.Contemporary clinical trials · 2015Trial
- The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: a randomized controlled trial.Psycho-oncology · 2015Trial
- How mindfulness changed my sleep: focus groups with chronic insomnia patients.BMC complementary and alternative medicine · 2014Trial
- Mindfulness-based stress reduction for family caregivers: a randomized controlled trial.The Gerontologist · 2013Trial
- Feasibility, acceptability, and effects of gentle Hatha yoga for women with major depression: findings from a randomized controlled mixed-methods study.Archives of psychiatric nursing · 2013Trial
- Mindfulness-based cognitive therapy improves polysomnographic and subjective sleep profiles in antidepressant users with sleep complaints.Psychotherapy and psychosomatics · 2012Trial
- Poor sleep in organ transplant recipients: self-reports and actigraphy.Clinical transplantationTrial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
contextPatients who have received solid organ transplants continue to experience a myriad of complex symptoms related to their underlying disease and to chronic immunosuppression that reduce the quality of life. Beneficial nonpharmacologic therapies to address these symptoms have not been established in the transplant population.
objectiveAssess the efficacy of mindfulness-based stress reduction (MBSR) in reducing symptoms of anxiety, depression, and poor sleep in transplant patients. DESIGN, SETTING, AND PATIENTS: Controlled trial with a two-staged randomization. Recipients of kidney, kidney/pancreas, liver, heart, or lung transplants were randomized to MBSR (n=72) or health education (n=66) initially or after serving in a waitlist. Mean age was 54 years (range 21-75); 55% were men, and 91% were white.
interventionsMBSR, a mindfulness meditation training program consisting of eight weekly 2.5-hour classes; health education, a peer-led active control. PRIMARY OUTCOME MEASURES: Anxiety (State-Trait Anxiety Inventory), depression (Center for Epidemiologic Studies Depression Scale), and sleep quality (Pittsburgh Sleep Quality Index) scales assessed by self-report at baseline, 8 weeks, 6 months, and 1 year.
resultsBenefits of MBSR were above and beyond those afforded by the active control. MBSR reduced anxiety and sleep symptoms (P < .02), with medium treatment effects (.51 and .56) at 1 year compared to health education in intention-to-treat analyses. Within the MBSR group, anxiety, depression, and sleep symptoms decreased and quality-of-life measures improved by 8 weeks (P < .01, all), and benefits were retained at 1 year (P < .05, all). Initial symptom reductions in the health education group were smaller and not sustained. Comparisons to the waitlist confirmed the impact of MBSR on both symptoms and quality of life, whereas health education improvements were limited to quality-of-life ratings.
conclusionsMBSR reduced distressing symptoms of anxiety, depression, and poor sleep and improved quality of life. Benefits were sustained over 1 year. A health education program provided fewer benefits, and effects were not as durable. MBSR is a relatively inexpensive, safe, and effective community-based intervention.
Indexed as
Identifiers
20882729PMC3076132W136267775What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.