ArticleJournal of magnetic resonance imaging : JMRI2010
In vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growth.
Article in Journal of magnetic resonance imaging : JMRI, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed, 66 citations in OpenAlex.
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- PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation.Circulation research · 2023Article
- Strain estimation in aortic roots from 4D echocardiographic images using medial modeling and deformable registration.Medical image analysis · 2023Article
- Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition.Scientific reports · 2022Article
- Molecular Imaging of Aortic Aneurysm and Its Translational Power for Clinical Risk Assessment.Frontiers in medicine · 2022Review
- The Association Between Curvature and Rupture in a Murine Model of Abdominal Aortic Aneurysm and Dissection.Experimental mechanics · 2021Article
- Translating mouse models of abdominal aortic aneurysm to the translational needs of vascular surgery.JVS-vascular science · 2021Review
- Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy.Disease models & mechanisms · 2020Article
- Recent Advances in Biomechanical Characterization of Thoracic Aortic Aneurysms.Frontiers in cardiovascular medicine · 2020Review
- Aortic Strain Correlates with Elastin Fragmentation in Fibrillin-1 Hypomorphic Mice.Circulation reports · 2019Article
- A preclinical ultrasound method for the assessment of vascular disease progression in murine models.Ultrasound (Leeds, England) · 2019Article
- Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions.Journal of visualized experiments : JoVE · 2019Article
- Anatomical location, sex, and age influence murine arterial circumferential cyclic strain before and during dobutamine infusion.Journal of magnetic resonance imaging : JMRI · 2019Article
- Gold nanoparticles that target degraded elastin improve imaging and rupture prediction in an AngII mediated mouse model of abdominal aortic aneurysm.Theranostics · 2019Article
- Cross-sectional area of the murine aorta linearly increases with increasing core body temperature.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018Article
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- Cardiac and respiratory-gated volumetric murine ultrasound.The international journal of cardiovascular imaging · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo develop methods to quantify cyclic strain, motion, and curvature of the murine abdominal aorta in vivo. MATERIALS AND
methodsC57BL/6J and apoE(-/-) mice underwent three-dimensional (3D) time-of-flight MR angiography to position cardiac-gated 2D slices at four locations along the abdominal aorta where circumferential cyclic strain and lumen centroid motion were calculated. From the 3D data, a centerline through the aorta was created to quantify geometric curvature at 0.1-mm intervals. Medial elastin content was quantified with histology postmortem. The location and shape of abdominal aortic aneurysms (AAAs), created from angiotensin II infusion, were evaluated qualitatively.
resultsStrain waveforms were similar at all locations and between groups. Centroid motion was significantly larger and more leftward above the renal vessels than below (P < 0.05). Maximum geometric curvature occurred slightly proximal to the right renal artery. Elastin content was similar around the circumference of the vessel. AAAs developed in the same location as the maximum curvature and grew in the same direction as vessel curvature and motion.
conclusionThe methods presented provide temporally and spatially resolved data quantifying murine aortic motion and curvature in vivo. This noninvasive methodology will allow serial quantification of how these parameters influence the location and direction of AAA growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.