ArticleIndian journal of anaesthesia2010
Non-cardiogenic pulmonary oedema after neostigmine given for reversal: A report of two cases.
Article in Indian journal of anaesthesia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Noncardiogenic Pulmonary Edema After Neostigmine Administration During Emergence From General Anesthesia: A Case Report.Case reports in anesthesiology · 2026Article
- Acute noncardiogenic pulmonary edema after neostigmine administration during the recovery period of general anesthesia: A case report.Medicine · 2018Article
- Neostigmine and pulmonary oedema.BMJ case reports · 2014Article
- Negative pressure pulmonary oedema: a rare case report of two brothers.Journal of clinical and diagnostic research : JCDR · 2013Article
- Pulmonary edema in myasthenic crisis.Case reports in critical care · 2013Article
- Anti-thymocyte globulin induced non-cardiogenic pulmonary edema during renal transplantation.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2011Article
- Could postoperative pulmonary oedema be attributed to the use of neostigmine?Indian journal of anaesthesia · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-cardiogenic pulmonary oedema (NCPE) is a clinical syndrome characterized by simultaneous presence of severe hypoxemia, bilateral alveolar infiltrates on chest radiograph, and no evidence of left atrial hypertension/congestive heart failure/fluid overload. The diagnosis of drug-related NCPE relies upon documented exclusion of other causes of NCPE like gastric aspiration, sepsis, trauma, negative pressure pulmonary oedema, etc. We describe two cases (45-year male and 6-year male), who had undergone elective surgery under general anaesthesia. They developed NCPE within 3-5 minutes after administration of 'neostigmine-glycopyrrolate' used to reverse residual neuromuscular blockade. Both patients were treated successfully with mechanical ventilatory support, and adjuvant therapy, viz., frusemide, dopamine, steroids. This report emphasizes that this fatal complication may be seen with neostigmine, the pathogenic mechanism remains unknown, and it probably is a drug-related NCPE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.