Evidence map›Paper›PMID 20879044›Full record

ReviewYonsei medical journal2010

Mast cells in allergic asthma and beyond.

Sebastian Reuter, Michael Stassen, Christian Taube

Open access · goldAbstract readReview
In one paragraph

Review in Yonsei medical journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The Role ofInternational journal of molecular sciences · 2022
    Review
  6. Correlation BetweenReports of biochemistry & molecular biology · 2022
    Article
  7. Review
  8. Mast Cells as Important Regulators in Autoimmunity and Cancer Development.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
  10. Asthma Phenotypes as a Guide for Current and Future Biologic Therapies.Clinical reviews in allergy & immunology · 2020
    Review
  11. Review
  12. Article
  13. Role of Polyamines in Asthma Pathophysiology.Medical sciences (Basel, Switzerland) · 2018
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Mast cell function: a new vision of an old cell.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2014
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sebastian ReuterIII Medical Clinic, Johannes Gutenberg-University, Langenbeckstr 1, 55131 Mainz, Germany. christian.taube@unimedizin-mainz.de
Michael Stassen
Christian Taube
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells have been regarded for a long time as effector cells in IgE mediated type I reactions and in host defence against parasites. However, they are resident in all environmental exposed tissues and express a wide variety of receptors, suggesting that these cells can also function as sentinels in innate immune responses. Indeed, studies have demonstrated an important role of mast cells during the induction of life-saving antibacterial responses. Furthermore, recent findings have shown that mast cells promote and modulate the development of adaptive immune responses, making them an important hinge of innate and acquired immunity. In addition, mast cells and several mast cell-produced mediators have been shown to be important during the development of allergic airway diseases. In the present review, we will summarize findings on the role of mast cells during the development of adaptive immune responses and highlight their function, especially during the development of allergic asthma.

Indexed as

AnimalsAnti-Infective AgentsAsthmaCytokinesHistamineHumansHypersensitivityImmune SystemImmunoglobulin ELeukotrienesMast CellsMiceModels, BiologicalProstaglandinsThymic Stromal LymphopoietinTumor Necrosis Factor-alphaAnti-Infective AgentsCytokinesHistamineImmunoglobulin ELeukotrienesProstaglandinsThymic Stromal LymphopoietinTumor Necrosis Factor-alpha

Identifiers

PMID20879044
PMCPMC2995967
OpenAlexW2120871131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.