ReviewJournal of genetic counseling2011
Can we make assumptions about the psychosocial impact of living as a carrier, based on studies assessing the effects of carrier testing?
Review in Journal of genetic counseling, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Trial
- Mothers' guilt responses to children's obesity risk feedback.Journal of health psychology · 2015Trial
- Psychosocial outcomes of reproductive genetic carrier screening up to five years post-result.European journal of human genetics : EJHG · 2026Article
- Experiences and insights of thalassaemia carriers from an indigenous community in Sabah, Malaysia.Journal of community genetics · 2025Article
- Understanding the psychological impact of identifying carrier status on young adults: A qualitative study exploring peer reactions.Journal of genetic counseling · 2025Article
- Couples' experiences with expanded carrier screening: evaluation of a university hospital screening offer.European journal of human genetics : EJHG · 2021Article
- "There Are Hills and Valleys": Experiences of Parenting a Son With X-Linked Retinoschisis.American journal of ophthalmology · 2020Article
- Parental Defensiveness about Multifactorial Genomic and Environmental Causes of Children's Obesity Risk.Childhood obesity (Print) · 2019Article
- Review
- Experiences of Women Who Have Had Carrier Testing for Duchenne Muscular Dystrophy and Becker Muscular Dystrophy During Adolescence.Journal of genetic counseling · 2018Article
- Reactions to clinical reinterpretation of a gene variant by participants in a sequencing study.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Expanded carrier screening in gamete donors of Venezuela.JBRA assisted reproduction · 2017Article
- "It was a lot Tougher than I Thought It would be". A Qualitative Study on the Changing Nature of Being a Hemophilia Carrier.Journal of genetic counseling · 2017Article
- Pre- and post-test genetic counseling for chromosomal and Mendelian disorders.Seminars in perinatology · 2016Review
- Changing trends in carrier screening for genetic disease in the United States.Prenatal diagnosis · 2015Review
- Effect of comprehensive oncogenetics training interventions for general practitioners, evaluated at multiple performance levels.PloS one · 2015Article
- How people in Benin assess a couple's risk of having a baby with sickle cell disease.Journal of community genetics · 2015Article
- From genetic counseling to "genomic counseling".Molecular genetics & genomic medicine · 2013Article
- Response to Stoll and Resta.Genetics in medicine : official journal of the American College of Medical Genetics · 2013Article
- Personal genome testing in medical education: student experiences with genotyping in the classroom.Genome medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Receiving the results of genetic carrier testing may have an impact on the psychosocial health of the individual. Numerous studies have been conducted to assess the psychosocial effects of carrier status for a range of conditions. To systematically review research focused on the psychological and social impact of carrier testing on individuals in order to identify factors affecting the impact of carrier testing results, and discern areas where further research is needed. Twenty relevant papers meeting criteria for inclusion in this review were found. The main themes identified across these studies included: anxiety, guilt and stigmatization, effect on family relationships, effect on self image, active coping mechanisms and reproductive issues. Variables related to the psychosocial effect of carrier testing included whether the carrier has an affected child, mode of inheritance, genetic counseling, and life stage. A key finding concerns carriers who already have an affected child; they are more likely to experience guilt and self-blame, and change their reproductive plans compared to carriers without affected children. Additionally, some participants reported clinical features of the disorder for which they were being tested. Genetic counselors may erroneously assume that parents with affected children are aware of their own carrier status in the absence of testing, and they may offer inadequate support. Additionally, counselors should attempt to address patient misconceptions related to their health and carrier status.
Indexed as
Identifiers
20878544What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.