Evidence map›Paper›PMID 20878326›Full record

ReviewPlant cell reports2011

Tail-anchored membrane proteins: exploring the complex diversity of tail-anchored-protein targeting in plant cells.

Ben M Abell, Robert T Mullen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant cell reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

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  13. Loss of GET pathway orthologs inProceedings of the National Academy of Sciences of the United States of America · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ben M AbellBiomedical Research Centre, Sheffield Hallam University, Howard Street, Sheffield, UK. b.abell@shu.ac.uk
Robert T Mullen
Sheffield Hallam University · GBUniversity of Guelph · CA

Funding

Biotechnology and Biological Sciences Research Council BB/E01559X/1
6 · The paper itself

Abstract

Tail-anchored (TA) proteins are special class of integral membrane proteins that in recent years have received a considerable amount of attention due to their diverse cellular functions and unique targeting and insertion mechanisms. Defined by the presence of a single, hydrophobic membrane-spanning domain at or near their C terminus, TA proteins must be inserted into membranes post-translationally and are orientated such that their larger N-terminal domain (most often the functional domain) faces the cytosol, while their shorter C-terminal domain faces the interior of the organelle. The C-terminal domain of TA proteins also usually contains the information responsible for their selective targeting to the proper subcellular membrane, a process that, based primarily on studies with yeasts and mammals, appears to be highly complex due to the presence of multiple pathways. Within this context, we discuss here the biogenesis of plant TA proteins and the potential for hundreds of new TA proteins identified via bioinformatics screens to contribute to the already remarkable number of roles that this class of membrane proteins participates in throughout plant growth and development.

Indexed as

OrganellesOrigin of LifeProtein Processing, Post-TranslationalProteomicsAmino Acid MotifsBiological EvolutionGene Expression Regulation, PlantGenome, PlantIntracellular MembranesMembrane ProteinsMolecular Sequence DataPlant DevelopmentPlant ProteinsPlantsProtein IsoformsProtein Sorting SignalsMembrane ProteinsPlant ProteinsProtein IsoformsProtein Sorting Signals

Identifiers

PMID20878326
OpenAlexW1979330256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.