Evidence map›Paper›PMID 20877780›Full record

ArticleLab on a chip2010

Design rules for pumping and metering of highly viscous fluids in microfluidics.

Sarah L Perry, Jonathan J L Higdon, Paul J A Kenis

Abstract read
In one paragraph

Article in Lab on a chip, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah L PerryUniversity of Illinois, Department of Chemical & Biomolecular Engineering, Urbana, IL 61801, USA.
Jonathan J L Higdon
Paul J A Kenis

Funding

On-Chip Crystallization and In Situ X-ray Analysis of Membrane ProteinsR01GM086727 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KENIS, PAUL J. A. · 2009 to 2011
$1.0M
Innovative Methods for Membrane Protein CrystallizationR21GM075930 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI KENIS, PAUL J A · 2005 to 2006
$358k
Microfluidic Membrane Protein Crystallization for HIgh Resolution ProteomicsF31EB008330 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PERRY, SARAH LOUISE · 2008 to 2009
$82k
NIBIB NIH HHS F31 EB008330NIGMS NIH HHS R01 GM086727NIGMS NIH HHS R21 GM075930
6 · The paper itself

Abstract

The use of fluids that are significantly more viscous than water in microfluidics has been limited due to their high resistance to flow in microscale channels. This paper reports a theoretical treatment for the flow of highly viscous fluids in deforming microfluidic channels, particularly with respect to transient effects, and discusses the implications of these effects on the design of appropriate microfluidic devices for highly viscous fluids. We couple theory describing flow in a deforming channel with design equations, both for steady-state flows and for the transient periods associated with the initial deformation and final relaxation of a channel. The results of this analysis allow us to describe these systems and also to assess the significance of different parameters on various deformation and/or transient effects. To exemplify their utility, we apply these design rules to two applications: (i) pumping highly viscous fluids for a nanolitre scale mixing application and (ii) precise metering of fluids in microfluidics.

Indexed as

MicrofluidicsComputer SimulationEquipment DesignMicrofluidic Analytical TechniquesModels, TheoreticalViscosity

Identifiers

PMID20877780
PMCPMC3598570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.