Evidence map›Paper›PMID 20877326›Full record

ArticleNature reviews. Genetics2010

Stochasticity versus determinism in development: a false dichotomy?

Magdalena Zernicka-Goetz, Sui Huang

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature reviews. Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Maps of variability in cell lineage trees.PLoS computational biology · 2019
    Article
  9. Differences in the Expression of TLR-2, NOD2, and NF-κB in Placenta Between Twins.Archivum immunologiae et therapiae experimentalis · 2018
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Totipotency: what it is and what it is not.Stem cells and development · 2014
    Article
  17. Review
  18. Review
  19. Cell lineage allocation within the inner cell mass of the mouse blastocyst.Results and problems in cell differentiation · 2012
    Review
  20. Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2011
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Magdalena Zernicka-GoetzThe Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK. m.zernicka-goetz@gurdon.cam.ac.uk
Sui Huang

Funding

Medical Research Council G0800784Wellcome Trust 064421
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic DeterminismStochastic ProcessesAnimalsCell DifferentiationEmbryo, MammalianEmbryonic DevelopmentGrowth and DevelopmentHumansMiceModels, StatisticalModels, TheoreticalResearch Design

Identifiers

PMID20877326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.