PRDM9 marks the spot.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes.Oncotarget · 2012
   Pooled it
2. The ectopic expression of meiCT genes promotes meiomitosis and may facilitate carcinogenesis.Cell cycle (Georgetown, Tex.) · 2020
   Review
3. Fast Estimation of Recombination Rates Using Topological Data Analysis.Genetics · 2019
   Article
4. Ruminant-specific multiple duplication events of PRDM9 before speciation.BMC evolutionary biology · 2017
   Article
5. What Use Is Population Genetics?Genetics · 2015
   Article
6. Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic drive.PLoS genetics · 2014
   Article
7. Rare allelic forms of PRDM9 associated with childhood leukemogenesis.Genome research · 2013
   Article
8. A comprehensive search for recombinogenic motifs in the human genome.PloS one · 2013
   Article
9. Population demographic history can cause the appearance of recombination hotspots.American journal of human genetics · 2012
   Article
10. High diversity at PRDM9 in chimpanzees and bonobos.PloS one · 2012
    Article
11. The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans.PLoS biology · 2011
    Review
12. On the origin of crossover interference: A chromosome oscillatory movement (COM) model.Molecular cytogenetics · 2011
    Article
13. Prdm9, a major determinant of meiotic recombination hotspots, is not functional in dogs and their wild relatives, wolves and coyotes.PloS one · 2011
    Article
14. Variation in human recombination rates and its genetic determinants.PloS one · 2011
    Article

Corrections and comments

• Comment on
  PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans.2010

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as