GWAS identifies a common breast cancer risk allele among BRCA1 carriers.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

1. Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.Human molecular genetics · 2014
   Pooled it
2. A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits.American journal of human genetics · 2012
   Pooled it
3. Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma.Cancer discovery · 2012
   Pooled it
4. Application of simulation-based CYP26 SNP-environment barcodes for evaluating the occurrence of oral malignant disorders by odds ratio-based binary particle swarm optimization: A case-control study in the Taiwanese population.PloS one · 2019
   Article
5. Meta-Analysis of SNP-Environment Interaction With Overlapping Data.Frontiers in genetics · 2019
   Article
6. Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease.Scientific reports · 2016
   Article
7. Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes and risk of breast cancer in China.Molecular genetics and genomics : MGG · 2015
   Article
8. The Combinational Polymorphisms of ORAI1 Gene Are Associated with Preventive Models of Breast Cancer in the Taiwanese.BioMed research international · 2015
   Article
9. Most common 'sporadic' cancers have a significant germline genetic component.Human molecular genetics · 2014
   Article
10. Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer.Cancer cell international · 2014
    Article
11. Human epidermal growth factor receptor 2 and estrogen receptor status in respect to tumor characteristics in non-metastatic breast cancer.Tanaffos · 2014
    Article
12. Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions.BioMed research international · 2014
    Article
13. Urinary bladder cancer susceptibility markers. What do we know about functional mechanisms?International journal of molecular sciences · 2013
    Review
14. MDR-ER: balancing functions for adjusting the ratio in risk classes and classification errors for imbalanced cases and controls using multifactor-dimensionality reduction.PloS one · 2013
    Article
15. Genetic susceptibility loci for subtypes of breast cancer in an African American population.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2013
    Article
16. Gene-gene interactions in breast cancer susceptibility.Human molecular genetics · 2012
    Article
17. An improved PSO algorithm for generating protective SNP barcodes in breast cancer.PloS one · 2012
    Article
18. Genome-wide association study identifies new prostate cancer susceptibility loci.Human molecular genetics · 2011
    Article
19. Genomic biomarkers in predictive medicine: an interim analysis.EMBO molecular medicine · 2011
    Review
20. Current status of genome-wide association studies in cancer.Human genetics · 2011
    Review

Corrections and comments

• Comment on
  A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.2010
• Comment on
  Common variants at 19p13 are associated with susceptibility to ovarian cancer.2010

Authors and funding

2 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as