ReviewJournal of genetics2010
Fruitless alternative splicing and sex behaviour in insects: an ancient and unforgettable love story?
Review in Journal of genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Characterization and analysis of the full-length transcriptome of Frankliniella occidentalis (Thysanoptera: Thripidae).BMC genomics · 2026Article
- The transformer gene controls sexual development in Drosophila suzukii.Insect science · 2026Article
- Butterfly brains change in morphology and in gene splicing patterns after brief pheromone exposure.BMC biology · 2026Article
- Understanding the genetics of sex determination in insects and its relevance to genetic pest management.Insect molecular biology · 2025Review
- Article
- Identification and Functional Analysis of theInsects · 2024Article
- The role ofScience advances · 2024Article
- Sex-Biased Expression Is Associated With Chromatin State in Drosophila melanogaster and Drosophila simulans.Molecular biology and evolution · 2023Article
- Theme and variation in the evolution of insect sex determination.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023Review
- Sex-biased expression is associated with chromatin state inbioRxiv : the preprint server for biology · 2023Article
- Article
- Doublesex regulates fruitless expression to promote sexual dimorphism of the gonad stem cell niche.PLoS genetics · 2021Article
- Transcriptome Analysis of Zebrafish Olfactory Epithelium Reveal Sexual Differences in Odorant Detection.Genes · 2020Article
- The fight to understand fighting: neurogenetic approaches to the study of aggression in insects.Current opinion in insect science · 2019Review
- Hemimetabolous insects elucidate the origin of sexual development via alternative splicing.eLife · 2019Article
- Identification of sex determination genes and their evolution in Phlebotominae sand flies (Diptera, Nematocera).BMC genomics · 2019Article
- Article
- De novo assembly and transcriptome analysis of the Mediterranean fruit fly Ceratitis capitata early embryos.PloS one · 2014Article
- Male-specific phosphorylated SR proteins in adult flies of the Mediterranean fruitfly Ceratitis capitata.BMC genetics · 2014Article
- Genetic control of courtship behavior in the housefly: evidence for a conserved bifurcation of the sex-determining pathway.PloS one · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Courtship behaviours are common features of animal species that reproduce sexually. Typically, males are involved in courting females. Insects display an astonishing variety of courtship strategies primarily based on innate stereotyped responses to various external stimuli. In Drosophila melanogaster, male courtship requires proteins encoded by the fruitless (fru) gene that are produced in different sex-specific isoforms via alternative splicing. Drosophila mutant flies with loss-of-function alleles of the fru gene exhibit blocked male courtship behaviour. However, various individual steps in the courtship ritual are disrupted in fly strains carrying different fru alleles. These findings suggest that fru is required for specific steps in courtship. In distantly related insect species, various fru paralogues were isolated, which shows conservation of sex-specific alternative splicing and protein expression in neural tissues and suggests an evolutionary functional conservation of fru in the control of male-specific courtship behaviour. In this review, we report the seminal findings regarding the fru gene, its splicing regulation and evolution in insects.
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