ReviewThe Plant cell2010
Endoplasmic reticulum protein quality control and its relationship to environmental stress responses in plants.
Review in The Plant cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 229 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
229 citing papers in PubMed, 454 citations in OpenAlex.
- Proteomic analysis may explain differences inPlant signaling & behavior · 2026Article
- Fusion Partner and ER-Retention Signal Are Associated with Distinct Host Proteomic and Metabolic Responses During Interleukin-15 Production inPlants (Basel, Switzerland) · 2026Article
- SIB1-SEC23A undergo ER to chloroplast relocalization to mediate immunity in Arabidopsis thaliana.Journal of integrative plant biology · 2026Article
- Suborbital spaceflight reveals rapid changes in gene expression accompanying the transition to and from space.NPJ microgravity · 2026Article
- Signal peptide peptidase-like proteases OsSPPL1 and OsSPPL2 facilitate ER-associated protein degradation in rice.Nature communications · 2026Article
- Transcriptome analysis coupled with virus induced gene silencing delineates the unfolded protein response of tomato.Molecular genetics and genomics : MGG · 2026Article
- Mining of genes and pathways associated with endoplasmic reticulum stress in Brassica campestris via RNA-Seq.Plant cell reports · 2026Article
- Multi-omics reveals DEAD-box RNA helicase 20 as key protein enhancing wilt resistance in transgenic chickpea.Plant cell reports · 2025Article
- Interplay between autophagy, the unfolded protein response and the cytoplasmic heat stress response during heat stress in maize.BMC plant biology · 2025Article
- Molecular cloning and the expression profile of two calnexin genes - CNX1 and CNX2 - during pollen development and pollen tube growth in Petunia.BMC plant biology · 2025Article
- The bZIP transcription factor RISBZ1 balances grain filling and ER stress response in rice grains.Plant communications · 2025Article
- SC35-mediated bZIP49 splicing regulates K⁺ channel AKT1 for salt stress adaptation in poplar.Nature communications · 2025Article
- Integrative Transcriptomic and Biochemical Analysis Reveals Key HSP20/Alpha-Crystallin Genes Associated with Heat Tolerance in Rice.Rice (New York, N.Y.) · 2025Article
- Comparative transcriptomic and proteomic analyses of hypoxia response in wild and cultivated tomato roots.BMC genomics · 2025Article
- Transcriptome time-course analysis unravels the regulatory networks governing ratooning decline in sugarcane.Frontiers in plant science · 2025Article
- Stress on the Endoplasmic Reticulum Impairs the Photosynthetic Efficiency of Chlamydomonas.International journal of molecular sciences · 2024Article
- Insights into the transcriptomic responses of silver-lipped pearl oysters Pinctada maxima exposed to a simulated large-scale seismic survey.BMC genomics · 2024Article
- Chromosome-scale genome assembly of Apocynum pictum, a drought-tolerant medicinal plant from the Tarim Basin.G3 (Bethesda, Md.) · 2024Article
- Cotton Bollworm (H. armigera) Effector PPI5 Targets FKBP17-2 to Inhibit ER Immunity and JA/SA Responses, Enhancing Insect Feeding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Expansion and diversification of the Glycine max (Gm) ERD15-like subfamily of the PAM2-like superfamily.Planta · 2024Article
169 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endoplasmic reticulum (ER) has a sophisticated quality control (QC) system to eliminate improperly folded proteins from the secretory pathway. Given that protein folding is such a fastidious process and subject to adverse environmental conditions, the ER QC system appears to have been usurped to serve as an environmental sensor and responder in plants. Under stressful conditions, the ER protein folding machinery reaches a limit as the demands for protein folding exceed the capacity of the system. Under these conditions, misfolded or unfolded proteins accumulate in the ER, triggering an unfolded protein response (UPR). UPR mitigates ER stress by upregulating the expression of genes encoding components of the protein folding machinery or the ER-associated degradation system. In Arabidopsis thaliana, ER stress is sensed and stress signals are transduced by membrane-bound transcription factors, which are activated and mobilized under environmental stress conditions. Under acute or chronic stress conditions, UPR can also lead to apoptosis or programmed cell death. Despite recent progress in our understanding of plant protein QC, discovering how different environmental conditions are perceived is one of the major challenges in understanding this system. Since the ER QC system is one among many stress response systems in plants, another major challenge is determining the extent to which the ER QC system contributes to various stress responses in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.