Evidence map›Paper›PMID 20876290›Full record

ArticleInfection and immunity2010

Reproducible science.

Arturo Casadevall, Ferric C Fang

Abstract readEditorial
In one paragraph

Article in Infection and immunity, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Big Data in Gastroenterology Research.International journal of molecular sciences · 2023
    Review
  10. A Practical Guide to Reproducible Modeling for Biochemical Networks.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Open science, communal culture, and women's participation in the movement to improve science.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Review
  16. Heat-KilledMolecules (Basel, Switzerland) · 2020
    Article
  17. Towards reproducible computational drug discovery.Journal of cheminformatics · 2020
    Review
  18. Automation in the Life Science Research Laboratory.Frontiers in bioengineering and biotechnology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arturo Casadevall
Ferric C Fang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reproducibility of an experimental result is a fundamental assumption in science. Yet, results that are merely confirmatory of previous findings are given low priority and can be difficult to publish. Furthermore, the complex and chaotic nature of biological systems imposes limitations on the replicability of scientific experiments. This essay explores the importance and limits of reproducibility in scientific manuscripts.

Indexed as

Reproducibility of ResultsBiomedical ResearchPublishing

Identifiers

PMID20876290
PMCPMC2981311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.