Evidence map›Paper›PMID 20876206›Full record

SynthesisDiabetes care2011

Physical activity before and during pregnancy and risk of gestational diabetes mellitus: a meta-analysis.

Deirdre K Tobias, Cuilin Zhang, Rob M van Dam, Katherine Bowers, Frank B Hu

4 registry-linked trialsOpen access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Diabetes care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 156 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed, 16 pooled it
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01675271 nacompletednot on this mapstarted 2012, after this paper: background citation

Effect Of Individual Exercise Prescription On Cardiovascular Risk Factors In Woman At Risk For Gestational Diabetes - Focus On Autonomic Nervous System And Inflammation

TypeinterventionalSponsorHelsinki University Central HospitalRan2012 to 2016Enrolled66ConditionsGestational Diabetes, Cardiovascular Risk FactorsArmsindividual exercise, general exercise
NCT02304718 nacompletednot on this mapstarted 2014, after this paper: background citation

Cycle Study:an Exercise Intervention to Prevent Gestational Diabetes in Overweight and Obese Chinese Pregnant Women

TypeinterventionalSponsorPeking University First HospitalRan2014 to 2016Enrolled300ConditionsGestational Diabetes MellitusArmsStationary bike
NCT05394883 nacompletednot on this mapstarted 2020, after this paper: background citation

The SPROUT (Pilot) Project: Starting Pregnancy With Robustness for Optimal Upward Trajectories

TypeinterventionalSponsorState University of New York - Upstate Medical UniversityRan2020 to 2022Enrolled18ConditionsPregnancy Related, Infant Development, Adherence, Treatment, Activity, MotorArmsSupervised Exercise, Home Exercise
NCT06452017 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Telerehabilitation Exercise Program on Maternal Antenatal Glycemic Control in Women With Gestational Diabetes.

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled70ConditionsGestational Diabetes Mellitus in PregnancyArmsTelerehabilitation exercise program, Routine medical care
3 · Its place in the literature

Who cites it

156 citing papers in PubMed, 16 syntheses or guidelines pooled it, 420 citations in OpenAlex.

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96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Deirdre K TobiasDepartment of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA. dbanel@hsph.harvard.edu
Cuilin Zhang
Rob M van Dam
Katherine Bowers
Frank B Hu
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USNational University of Singapore · SGHarvard University · US

Funding

Risk Factors of Gestational DiabetesZIAHD008889 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YEUNG, EDWINA · 2009 to 2022
$1.4M
Intramural NIH HHS
6 · The paper itself

Abstract

objectiveGestational diabetes mellitus (GDM) is one of the most common complications of pregnancy and is associated with a substantially elevated risk of adverse health outcomes for both mothers and offspring. Physical activity may contribute to the prevention of GDM and thus is crucial for dissecting the vicious circle involving GDM, childhood obesity, and adulthood obesity, and diabetes. Therefore, we aimed to systematically review and synthesize the current evidence on the relation between physical activity and the development of GDM. RESEARCH DESIGN AND

methodsMedline, EMBASE, and Cochrane Reviews were searched from inception to 31 March 2010. Studies assessing the relationship between physical activity and subsequent development of GDM were included. Characteristics including study design, country, GDM diagnostic criteria, ascertainment of physical activity, timing of exposure (prepregnancy or early pregnancy), adjusted relative risks, CIs, and statistical methods were extracted independently by two reviewers.

resultsOur search identified seven prepregnancy and five early pregnancy studies, including five prospective cohorts, two retrospective case-control studies, and two cross-sectional study designs. Prepregnancy physical activity was assessed in 34,929 total participants, which included 2,813 cases of GDM, giving a pooled odds ratio (OR) of 0.45 (95% CI 0.28-0.75) when the highest versus lowest categories were compared. Exercise in early pregnancy was assessed in 4,401 total participants, which included 361 cases of GDM, and was also significantly protective (0.76 [95% CI 0.70-0.83]).

conclusionsHigher levels of physical activity before pregnancy or in early pregnancy are associated with a significantly lower risk of developing GDM.

Indexed as

Diabetes, GestationalFemaleHumansMotor ActivityPregnancy

Identifiers

PMID20876206
PMCPMC3005457
OpenAlexW2127377417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.