ArticleDiabetes care2011
Prevalence and correlates of latent autoimmune diabetes in adults in Tianjin, China: a population-based cross-sectional study.
Article in Diabetes care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The worldwide prevalence of latent autoimmune diabetes of adults among adult-onset diabetic individuals: a systematic review and meta-analysis.Endocrine · 2023Pooled it
- Type B insulin resistance syndrome induced by systemic lupus erythematosus and successfully treated with intravenous immunoglobulin: case report and systematic review.Clinical rheumatology · 2013Pooled it
- Evaluation of distinct and similar pathological features between diabetes and Alzheimer's disease.EXCLI journal · 2026Review
- Latent Autoimmune Diabetes in Adults: A Case Report.Oman medical journal · 2024Article
- Differential Associations of GAD Antibodies (GADA) and C-Peptide With Insulin Initiation, Glycemic Responses, and Severe Hypoglycemia in Patients Diagnosed With Type 2 Diabetes.Diabetes care · 2023Article
- Adult-onset autoimmune diabetes.Nature reviews. Disease primers · 2022Review
- Prevalence and factors associated with latent autoimmune diabetes in adults (LADA): a cross-sectional study.BMC endocrine disorders · 2022Article
- Latent autoimmune diabetes in adults in China.Frontiers in immunology · 2022Review
- Fatty Acid Profiles and Their Association With Autoimmunity, Insulin Sensitivity and β Cell Function in Latent Autoimmune Diabetes in Adults.Frontiers in endocrinology · 2022Article
- Latent Autoimmune Diabetes in Adults and Metabolic Syndrome-A Mini Review.Frontiers in endocrinology · 2022Review
- Development and Validation of a Prevalence Model for Latent Autoimmune Diabetes in Adults (LADA) Among Patients First Diagnosed with Type 2 Diabetes Mellitus (T2DM).Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Low rate of latent autoimmune diabetes in adults (LADA) in patients followed for type 2 diabetes: A single center's experience in Turkey.Archives of endocrinology and metabolism · 2021Article
- Latent Autoimmune Diabetes in Adults (LADA) and its Metabolic Characteristics among Yemeni Type 2 Diabetes Mellitus Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Slowly Progressive Type 1 Diabetes Mellitus: Current Knowledge And Future Perspectives.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Review
- Latent Autoimmune Diabetes in Adults: A Review on Clinical Implications and Management.Diabetes & metabolism journal · 2018Review
- Latent Autoimmune Diabetes in Adults: Current Status and New Horizons.Endocrinology and metabolism (Seoul, Korea) · 2018Review
- Adult-onset autoimmune diabetes: current knowledge and implications for management.Nature reviews. Endocrinology · 2017Review
- Pre- and undiagnosed-hypertension in urban Chinese adults: a population-based cross-sectional study.Journal of human hypertension · 2017Article
- Prevalence of Overweight and Obesity among Chinese Adults: Role of Adiposity Indicators and Age.Obesity facts · 2016Article
- Variation of C peptide decay rate in diabetic patients with positive glutamic acid decarboxylase antibody: better discrimination with initial fasting C peptide.BMC endocrine disorders · 2013Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveData on latent autoimmune diabetes in adults (LADA) from population-based studies are sparse. We sought to investigate the prevalence and correlates of LADA. RESEARCH DESIGN AND
methodsA total of 8,109 participants, who were aged ≥15 years and living in Tianjin, China, were assessed to identify individuals with type 2 diabetes (American Diabetes Association Criteria, 1997) and further to detect patients with LADA. LADA was ascertained by 1) the presence of type 2 diabetes and age ≥35 years, 2) the lack of a requirement for insulin at least 6 months after the diagnosis of type 2 diabetes, and 3) serum GAD antibody positivity. Data were analyzed using multinomial logistic regression with adjustment for potential confounders.
resultsOf all participants, 498 (6.1%) were patients with type 2 diabetes. Of them, 46 (9.2%) were found to have LADA. The prevalence of LADA was 0.6% (46 of 8,109), and tended to increase with age up to 50-59 years in all participants. The odds ratios (95% CI) of LADA related to hypertension, family history of diabetes, waist-to-hip ratio ≥0.85, and major stressful events were 1.93 (1.02-3.65), 17.59 (9.08-34.06), 5.37 (2.31-12.49), and 4.09 (1.75-9.52), respectively.
conclusionsThe prevalence of LADA is ∼9% in patients with type 2 diabetes. Hypertension, family history of diabetes, central obesity, and major stressful events may be associated with the occurrence of LADA.
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