ArticleDiabetes care2011
Extended family history of diabetes and autoimmune diseases in children with and without type 1 diabetes.
Article in Diabetes care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 23 citations in OpenAlex.
- Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.Diabetologia · 2026Observational
- Gestational diabetes and parental type 2 diabetes as risk indicators for type 1 diabetes in offspring: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Family history of type 2 diabetes and characteristics of children with newly diagnosed type 1 diabetes.Diabetologia · 2021Observational
- Extended family history of type 1 diabetes in HLA-predisposed children with and without islet autoantibodies.Pediatric diabetes · 2020Article
- Extended family history of type 1 diabetes and phenotype and genotype of newly diagnosed children.Diabetes care · 2013Article
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Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the extended family history of diabetes or autoimmune diseases in families with and without children having type 1 diabetes. RESEARCH DESIGN AND
methodsThree hundred case families and 381 control families were interviewed using structured questionnaires.
resultsThe proportion of case children having at least one relative with type 1 diabetes outside the nuclear family was higher than that of control children (50.3 vs. 31.8%, P < 0.001). The proportions of case and control children having relatives with type 2 diabetes or gestational diabetes were similar. Other autoimmune diseases occurred more frequently among the case children (9.7 vs. 1.1%, P < 0.001), in the case nuclear families (22.0 vs. 12.9%, P = 0.002) and in relatives outside the case nuclear family (72.0 vs. 62.2%, P = 0.007).
conclusionsType 1 diabetes and autoimmune diseases not only cluster in the nuclear families of children with type 1 diabetes but are also overrepresented in their extended families.
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Registered trials
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