ArticleEnvironmental health perspectives2011
Sharing unexpected biomarker results with study participants.
Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Outcomes from Returning Individual versus Only Study-Wide Biomonitoring Results in an Environmental Exposure Study Using the Digital Exposure Report-Back Interface (DERBI).Environmental health perspectives · 2021Trial
- Ethical, Legal, and Social Implications of Gene-Environment Interaction Research.Genetic epidemiology · 2025Review
- Moving Forward with Reporting Back Individual Environmental Health Research Results.Environmental health perspectives · 2023Article
- Article
- Environmental exposures during windows of susceptibility for breast cancer: a framework for prevention research.Breast cancer research : BCR · 2019Review
- Results Communication in Breast Milk Biomonitoring Studies: A Scoping Review and Stakeholder Consultation.Health and human rights · 2019Article
- Comprehension and perceptions of study participants upon receiving perfluoroalkyl substance exposure biomarker results.International journal of hygiene and environmental health · 2018Article
- Communicating environmental exposure results and health information in a community-based participatory research study.BMC public health · 2018Article
- Researcher and institutional review board perspectives on the benefits and challenges of reporting back biomonitoring and environmental exposure results.Environmental research · 2017Article
- DERBI: A Digital Method to Help Researchers Offer "Right-to-Know" Personal Exposure Results.Environmental health perspectives · 2017Article
- Community Engagement and Research Translation in Puerto Rico's Northern Karst Region: The PROTECT Superfund Research Program.New solutions : a journal of environmental and occupational health policy : NS · 2016Article
- Communicating results in post-Belmont era biomonitoring studies: lessons from genetics and neuroimaging research.Environmental research · 2015Review
- Environmental Research Translation: enhancing interactions with communities at contaminated sites.The Science of the total environment · 2014Article
- Changes in serum concentrations of maternal poly- and perfluoroalkyl substances over the course of pregnancy and predictors of exposure in a multiethnic cohort of Cincinnati, Ohio pregnant women during 2003-2006.Environmental science & technology · 2014Article
- Reporting individual results for biomonitoring and environmental exposures: lessons learned from environmental communication case studies.Environmental health : a global access science source · 2014Article
- Disclosure of individualized research results: a precautionary approach.Accountability in research · 2011Article
- Product biomonitoring and responsible reporting.Environmental health perspectives · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThe Breast Cancer and the Environment Research Centers (BCERCs) include collaborators from basic sciences, epidemiology, and the community, conducting studies to investigate whether environmental exposures are associated with the timing of puberty. A pilot study of a subset of the study participants assessed the feasibility of measuring selected biomarkers of exposure in blood and urine in girls 6-8 years of age. In the Greater Cincinnati study population, we found an elevated serum concentration of perfluorooctanoate (PFOA) among > 90% of young girls living in a small community.
objectivesThe research team deliberated whether and how to report the PFOA findings to our study families. We will address the issues considered in our decision, as well as the formats we used to present the findings.
methodsThe results were verified as we searched for potential sources of the elevated PFOA levels. As a research team, we grappled with issues regarding the reporting of unexpected results, derived from unknown sources and with unknown clinical significance. Ultimately, we did decide to present these findings to the study families through a well-developed communication plan. DISCUSSION: Research team members came from a variety of experiences and backgrounds, which led to different interpretations about the clinical, ethical, and public health issues surrounding these findings. The ethical debates centered around the precautionary principle, the right to know, and do no harm.
conclusionsGiven advances in environmental biomarker technologies and greater use of the transdisciplinary research model, a communication plan must be developed for those involved as study participants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.