ReviewRespiratory care2010
Sleep-disordered breathing and COPD: the overlap syndrome.
Review in Respiratory care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Long-Term Noninvasive Ventilation in Chronic Stable Hypercapnic Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Highly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPD.International journal of chronic obstructive pulmonary disease · 2016Trial
- Precision Medicine in Overlap Syndrome (COPD-Obstructive Sleep Apnea): From Phenotypes and Endotypes to Treatable Traits.Advances in respiratory medicine · 2026Review
- Association of obstructive airway disease with COMISA: findings from the Turkish sleep apnea database (TURKAPNE) cohort.Sleep & breathing = Schlaf & Atmung · 2026Observational
- Management of Patients with Asthma, COPD, and OSA in Outpatient Unit: ACOSOU-Global Perspectives and Challenges.Pulmonary therapy · 2026Review
- Beyond the apnea-hypopnea index in COPD-OSA overlap syndrome: a mechanism-informed framework for nocturnal oxygenation and ventilation.Frontiers in physiology · 2026Review
- Treatment With Bilevel PAP Is Associated With a Reduction in Severe Exacerbations in COPD-OSA Overlap: A Retrospective Claims Analysis.CHEST pulmonary · 2025Article
- Adaptive non-invasive ventilation treatment for sleep apnea.Healthcare technology letters · 2024Article
- Nocturnal Hypoxemia Is Associated with Sarcopenia in Patients with Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2024Article
- Knowledge and Attitudes Toward Obstructive Sleep Apnea Among Korean Pulmonologists: A Nationwide Survey.Cureus · 2024Article
- A Data-Driven Framework for Clinical Decision Support Systems in Positive Airway Pressure and Oxygen Titration.Journal of clinical medicine · 2024Article
- Diabetic retinopathy is a predictor of chronic respiratory failure: A nationwide register-based cohort study.Heliyon · 2023Article
- The Role of Inverted Papilloma Surgical Removal for Sleep Apnea Treatment Success-A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Clinical Evaluation and Management of Overlap Syndrome (OS) and Obesity Hypoventilation Syndrome (OHS).Clocks & sleep · 2022Article
- Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits.PLoS genetics · 2022Article
- Circadian clock gene Clock-Bmal1 regulates cellular senescence in Chronic obstructive pulmonary disease.BMC pulmonary medicine · 2022Article
- Vitamin D Levels in Patients with Overlap Syndrome, Is It Associated with Disease Severity?Journal of personalized medicine · 2022Article
- Effect of Two Interventional Strategies on Improving Continuous Positive Airway Pressure Adherence in Existing COPD and Obstructive Sleep Apnea Patients: The O2VERLAP Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Article
- Sleep disorders and COVID-19.Sleep medicine · 2022Article
- Smoking Obstructive Sleep Apnea: Arguments for a Distinctive Phenotype and a Personalized Intervention.Journal of personalized medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Sleep-disordered breathing (mainly obstructive sleep apnea [OSA]) and COPD are among the most common pulmonary diseases, so a great number of patients have both disorders; this "overlap syndrome" causes more severe nocturnal hypoxemia than either disease alone. This common combination of OSA and COPD has important implications for diagnosis, treatment, and outcome. Specifically, patients with COPD and OSA have a substantially greater risk of morbidity and mortality, compared to those with either COPD or OSA alone. Only now are the interactions between these 2 systemic diseases being determined and appreciated. Many questions remain, however, with regard to disease definition, prognosis, and optimal treatment. Treatment currently consists of continuous positive airway pressure, and oxygen as needed. Noninvasive ventilation may be helpful in overlap syndrome patients, but this has not yet been well studied.
Indexed as
Identifiers
20875160PMC3387564W2096426160What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.