ReviewCNS neuroscience & therapeutics2010
Peculiarities of geriatric psychiatry: a focus on aging and depression.
Review in CNS neuroscience & therapeutics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of traditional Chinese mind-body exercises on depressive symptoms in middle-aged and older adults: a multilevel meta-analysis with exploratory dose-response and machine learning analyses.Frontiers in psychology · 2026Pooled it
- Peripheral Inflammatory Parameters in Late-Life Depression: A Systematic Review.International journal of molecular sciences · 2016Pooled it
- Associations of physical, psychological, and cognitive multimorbidity with health service utilisation and catastrophic health expenditure among middle-aged and older adults: a longitudinal study in China.Archives of public health = Archives belges de sante publique · 2026Article
- Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.Journal of agricultural and food chemistry · 2023Article
- Among Gerontogens, Heavy Metals Are a Class of Their Own: A Review of the Evidence for Cellular Senescence.Brain sciences · 2023Review
- Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Article
- The Impact of Translational Neuroscience on Revisiting Psychiatric Diagnosis: State of the Art and Conceptual Analysis.Balkan medical journal · 2017Review
- Article
- Association between altered resting-state cortico-cerebellar functional connectivity networks and mood/cognition dysfunction in late-onset depression.Journal of neural transmission (Vienna, Austria : 1996) · 2015Article
- Frequency-dependent amplitude alterations of resting-state spontaneous fluctuations in late-onset depression.BioMed research international · 2015Article
- Abnormal functional connectivity of amygdala in late-onset depression was associated with cognitive deficits.PloS one · 2013Article
- Cerebrospinal fluid biomarkers in Alzheimer's disease and geriatric depression: preliminary findings from Brazil.CNS neuroscience & therapeutics · 2012Article
- Sixteen-month evaluation of depressive symptomatology in older adults.Archives of psychiatric nursing · 2012Article
- Specifying the neuropsychology of affective disorders: clinical, demographic and neurobiological factors.Neuropsychology review · 2011Review
- Acute exercise improves cognition in the depressed elderly: the effect of dual-tasks.Clinics (Sao Paulo, Brazil) · 2011Article
- Effects of motor and cognitive dual-task performance in depressive elderly, healthy older adults, and healthy young individuals.Dementia & neuropsychologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a debate on whether Geriatric Psychiatry stands for itself as a discrete specialty or whether it is an extension of clinical Geriatrics, Neurology, and Psychiatry. This review aims to outline some recent data and possible approaches to define peculiarities of Geriatric Psychiatry, focusing on certain characteristics that define the aging brain. Geriatric depression is discussed taking into consideration some data from translational research. The brain aging process is not uniform. Frontal areas show marked impairment in inhibiting irrelevant information in working memory as they age, and the recruitment of these areas occur differently than in young subjects. Executive functions also change in normal elderly. Geriatric depression is a general definition of a multidimensional disorder with multiple risk factors. Dysexecutive syndrome is considered as a key to the neuropsychology of geriatric depression, correlated with functional impairment in late life. Late-onset depression has a higher load of comordibity, of cerebrovascular disease, and of some genetic factors that may be different from early onset depression. Also, there are at least four clusters of treatment outcomes that are common in geriatric depression, which mirror the neuropsychological and clinical profiles. Research and practice in Geriatric Psychiatry should focus on the interaction of various dimensions and risk factors rather than on attempting to find a single cause to the disorders. Some answers may be found in comorbidity issues, in white matter lesions, which are more common in the elderly, and in genetic factors that impact on the aging process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.