Evidence map›Paper›PMID 20872994›Full record

ArticleExperimental dermatology2010

The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasms.

Joel Pinczewski, Andrzej Slominski

Open access · bronzeAbstract read
In one paragraph

Article in Experimental dermatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Current Molecular Markers of Melanoma and Treatment Targets.International journal of molecular sciences · 2020
    Review
  3. Review
  4. Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.Drug metabolism and disposition: the biological fate of chemicals · 2013
    Article
  5. Article
  6. Article
  7. Article
  8. New vitamin D analogs as potential therapeutics in melanoma.Expert review of anticancer therapy · 2012
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Joel PinczewskiDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
Andrzej Slominski
University of Maryland, Baltimore · USUniversity of Tennessee Health Science Center · US

Funding

Novel Biosynthetic Pathway for Secosteroids and the SkinR01AR052190 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI POSTLETHWAITE, ARNOLD E, SLOMINSKI, ANDRZEJ T · 2006 to 2013
$2.2M
NIAMS NIH HHS AR052190NIAMS NIH HHS R01 AR052190
6 · The paper itself

Abstract

Hormonally active vitamin D3, 1,25-(OH)2D3, is believed to have a role in the prevention of cancer formation and in limiting the aggressiveness of cancers that do arise. Therefore,much interest is presently being focused on 1,25-(OH)2D3 and its analogues as potential treatments for various cancers including melanoma. This article discusses the evidence in favour of a role for 1,25-(OH)2D3 in protection against the progression of melanocytic lesions and also summarizes the mechanisms by which 1,25-(OH)2D3 may act to protect against melanoma development and progression.

Indexed as

HumansMelanomaRisk FactorsSkin NeoplasmsVitamin DVitamin D

Identifiers

PMID20872994
PMCPMC2947742
OpenAlexW1540236839

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.