ArticleProceedings of the National Academy of Sciences of the United States of America2010
Global effects of the small RNA biogenesis machinery on the Arabidopsis thaliana transcriptome.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 69 citations in OpenAlex.
- Capture of regulatory factors via CRISPR-dCas9 for mechanistic analysis of fine-tuned SERRATE expression in Arabidopsis.Nature plants · 2024Article
- Intrinsically disordered proteins SAID1/2 condensate on SERRATE for dual inhibition of miRNA biogenesis in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Transcriptional and post-transcriptional regulation of RNAi-related gene expression during plant-virus interactions.Stress biology · 2022Review
- An insight into microRNA biogenesis and its regulatory role in plant secondary metabolism.Plant cell reports · 2022Review
- PRP4KA phosphorylates SERRATE for degradation via 20Science advances · 2022Article
- RNAi-Based Antiviral Innate Immunity in Plants.Viruses · 2022Review
- Current understanding of the interplays between host hormones and plant viral infections.PLoS pathogens · 2021Review
- Degradation of SERRATE via ubiquitin-independent 20S proteasome to survey RNA metabolism.Nature plants · 2020Article
- DCL-suppressed Nicotiana benthamiana plants: valuable tools in research and biotechnology.Molecular plant pathology · 2019Article
- Arabidopsis RNA processing factor SERRATE regulates the transcription of intronless genes.eLife · 2018Article
- Abscisic Acid Induces Resistance againstPlant physiology · 2017Article
- Combined Activity of DCL2 and DCL3 Is Crucial in the Defense against Potato Spindle Tuber Viroid.PLoS pathogens · 2016Article
- Mobile small RNAs regulate genome-wide DNA methylation.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Roles of plant hormones in the regulation of host-virus interactions.Molecular plant pathology · 2015Review
- microRNA biogenesis, degradation and activity in plants.Cellular and molecular life sciences : CMLS · 2015Review
- The dicer-like1 homolog fuzzy tassel is required for the regulation of meristem determinacy in the inflorescence and vegetative growth in maize.The Plant cell · 2014Article
- MiRNAting control of DNA methylation.Journal of biosciences · 2014Article
- RNA-seq analysis identifies an intricate regulatory network controlling cluster root development in white lupin.BMC genomics · 2014Article
- Global and local perturbation of the tomato microRNA pathway by a trans-activated DICER-LIKE 1 mutant.Journal of experimental botany · 2014Article
- RACK1 and the microRNA pathway: is it déjà-vu all over again?Plant signaling & behavior · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Arabidopsis thaliana, four different dicer-like (DCL) proteins have distinct but partially overlapping functions in the biogenesis of microRNAs (miRNAs) and siRNAs from longer, noncoding precursor RNAs. To analyze the impact of different components of the small RNA biogenesis machinery on the transcriptome, we subjected dcl and other mutants impaired in small RNA biogenesis to whole-genome tiling array analysis. We compared both protein-coding genes and noncoding transcripts, including most pri-miRNAs, in two tissues and several stress conditions. Our analysis revealed a surprising number of common targets in dcl1 and dcl2 dcl3 dcl4 triple mutants. Furthermore, our results suggest that the DCL1 is not only involved in miRNA action but also contributes to silencing of a subset of transposons, apparently through an effect on DNA methylation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.