ArticleJournal of bacteriology2010
The Staphylococcus aureus autoinducer-2 synthase LuxS is regulated by Ser/Thr phosphorylation.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Natural Phenolics Disrupt Microbial Communication by Inhibiting Quorum Sensing.Microorganisms · 2025Article
- Maintenance of heme homeostasis inJournal of bacteriology · 2023Article
- Therapeutic Strategies against Biofilm Infections.Life (Basel, Switzerland) · 2023Review
- Quorum Sensing, Biofilm, and Intestinal Mucosal Barrier: Involvement the Role of Probiotic.Frontiers in cellular and infection microbiology · 2020Review
- Biofilms: Architecture, Resistance, Quorum Sensing and Control Mechanisms.Indian journal of microbiology · 2019Review
- Anti-Biofilm Activity of a Long-Chain Fatty Aldehyde from AntarcticFrontiers in cellular and infection microbiology · 2017Article
- Regulatory Requirements for Staphylococcus aureus Nitric Oxide Resistance.Journal of bacteriology · 2016Article
- Exploration of Modulated Genetic Circuits Governing Virulence Determinants in Staphylococcus aureus.Indian journal of microbiology · 2016Review
- Molecular Events for Promotion of Vancomycin Resistance in Vancomycin IntermediateFrontiers in microbiology · 2016Review
- Environmental Sensing in Actinobacteria: a Comprehensive Survey on the Signaling Capacity of This Phylum.Journal of bacteriology · 2015Article
- ArtR, a novel sRNA of Staphylococcus aureus, regulates α-toxin expression by targeting the 5' UTR of sarT mRNA.Medical microbiology and immunology · 2014Article
- A novel mode of regulation of the Staphylococcus aureus catabolite control protein A (CcpA) mediated by Stk1 protein phosphorylation.The Journal of biological chemistry · 2012Article
- Genetic regulation of the intercellular adhesion locus in staphylococci.Frontiers in cellular and infection microbiology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Staphylococcus aureus autoinducer-2 (AI-2) producer protein LuxS is phosphorylated by the Ser/Thr kinase Stk1 at a unique position, Thr14. The enzymatic activity of the phosphorylated isoform of LuxS was abrogated compared to that of nonphosphorylated LuxS, thus providing the first evidence of an AI-2-producing enzyme regulated by phosphorylation and demonstrating that S. aureus possesses an original and specific system for controlling AI-2 synthesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.