Evidence map›Paper›PMID 20869406›Full record

ReviewVirus research2011

The role of cytomegalovirus in angiogenesis.

Patrizia Caposio, Susan L Orloff, Daniel N Streblow

Abstract readReview
In one paragraph

Review in Virus research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Does human cytomegalovirus provide a novel therapeutic target for patients with glioblastoma?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  4. Review
  5. The Interplay Between Immunity, Inflammation and Endothelial Dysfunction.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Overview of Human Cytomegalovirus Pathogenesis.Methods in molecular biology (Clifton, N.J.) · 2021
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Patrizia CaposioDepartment of Molecular Microbiology & Immunology and The Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Susan L Orloff
Daniel N Streblow
Oregon Health & Science University · USPortland VA Medical Center · US

Funding

The role of CMV secretome in the acceleration of transplant vascular sclerosisR01HL088603 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NELSON, JAY A · 2008 to 2012
$3.6M
Cytomegalovirus Chemokine Receptors in Transplant Vascular SclerosisR01HL085451 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORLOFF, SUSAN L · 2009 to 2013
$2.2M
Mechanisms of CMV latency in accelerated vascular diseaseR01HL083194 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI STREBLOW, DANIEL N · 2006 to 2010
$1.5M
NHLBI NIH HHS HL 083194NHLBI NIH HHS HL 085451NHLBI NIH HHS HL 088603NHLBI NIH HHS R01 HL083194NHLBI NIH HHS R01 HL085451NHLBI NIH HHS R01 HL088603
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) infection has been associated with the acceleration of vascular disease including atherosclerosis and transplant associated vasculopathy in solid organ transplants. HCMV promotes vascular disease at many of the different stages of the disease development. These include the initial injury phase, enhancing the response to injury and inflammation, as well as by increasing SMC hyperplasia and foamy macrophage cell formation. Angiogenesis is a critical process involved in the development of vascular diseases. Recently, HCMV has been shown to induce angiogenesis and this process is thought to contribute to HCMV-accelerated vascular disease and may also be important for HCMV-enhanced tumor formation. This review will highlight the role of HCMV in promoting angiogenesis.

Indexed as

Neovascularization, PathologicBasement MembraneBlood VesselsCell MovementChronic DiseaseCytomegalovirusCytomegalovirus InfectionsEndothelial CellsHumansVascular DiseasesVascular Endothelial Growth Factor AVascular Endothelial Growth Factor A

Identifiers

PMID20869406
PMCPMC3040784
OpenAlexW2085235429

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.