ArticlePhysical review. E, Statistical, nonlinear, and soft matter physics2010
Molecular origin of strain softening in cross-linked F-actin networks.
Article in Physical review. E, Statistical, nonlinear, and soft matter physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Multiscale architecture: Mechanics of composite cytoskeletal networks.Biophysics reviews · 2022Review
- Actin Stress Fibers Response and Adaptation under Stretch.International journal of molecular sciences · 2022Article
- Mechanical competition alters the cellular interpretation of an endogenous genetic program.The Journal of cell biology · 2021Article
- Large Amplitude Oscillatory Shear Rheology of Living Fibroblasts: Path-Dependent Steady States.Biophysical journal · 2017Article
- Microrheology of highly crosslinked microtubule networks is dominated by force-induced crosslinker unbinding.Soft matter · 2013Article
- Article
- Polymer physics of the cytoskeleton.Current opinion in solid state & materials science · 2011Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Two types of measurement are presented that relate molecular events to macroscopic behavior of F-actin networks. First, shear modulus is measured by oscillating an embedded microbead. Second, a microbead is translated at constant rate and transitions in the resisting force are observed. The loading rate dependence of the force at the transitions is similar to that of the molecular unbinding force, suggesting that they share a common origin. Reversibility tests of shear modulus provide further evidence that strain softening of F-actin networks is caused by force-induced rupture of cross-links.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.