Evidence map›Paper›PMID 20865469›Full record

ReviewInternal and emergency medicine2010

Chronic migraine: comorbidities, risk factors, and rehabilitation.

Andrea Negro, Lidia D'Alonzo, Paolo Martelletti

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05568004 (The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05568004 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine :Randomized Controlled Study

TypeinterventionalSponsorEge UniversityRan2022 to 2024Enrolled32ConditionsMigraine, Chronic MigraineArmsCombined exercise, Aerobic exercise
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Vitamin D in migraine headache: a comprehensive review on literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Pooled it
  2. Maternal migraine and risk of pediatric cancers.Pediatric blood & cancer · 2023
    Article
  3. Review
  4. Association of dietary diversity score (DDS) and migraine headache severity among women.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  5. The effect of greater occipital nerve blockade on the quality of life, disability and comorbid depression, anxiety, and sleep disturbance in patients with chronic migraine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  6. Review
  7. Observational
  8. Review
  9. Article
  10. Review
  11. Quarterly repeat cycles of onabotulinumtoxinA in chronic migraine patients: the benefits of the prolonged treatment on the continuous responders and quality-of-life conversion rate in a real-life setting.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
  12. A Critical Evaluation on MOH Current Treatments.Current treatment options in neurology · 2017
    Review
  13. Review
  14. Managing migraine by patient profile: role of frovatriptan.Patient preference and adherence · 2016
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea NegroRegional Referral Headache Centre and Internal Medicine, Department of Clinical and Molecular Sciences, II School of Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035, 00189, Rome, Italy.
Lidia D'Alonzo
Paolo Martelletti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is a serious illness with a spontaneous clinical evolution into a chronic form. In some episodic migraines, increase of crises frequency modifies the headache pattern in the chronic form, defined as chronic migraine (CM), with headache frequency of 15 days/month. One-year prevalence of CM includes around 2-4% of the general population. Migraine progression from episodic to chronic form is realized through a period of time involving several months or years, during which an increase of attack frequency occurs. Migraine shows a wide spectrum of comorbidities, including cardiocerebral, vascular, psychiatric, metabolic, neurologic as well as other pathologies. The single/multiple presence of such comorbidities represents a fixed factor in the process of chronicization into CM. Risk factors including medication overuse headache (MOH), obesity, and lifestyle cooperate in the evolution process to CM. MOH is the most severe complication of CM, and similarly to CM its appearance is gradual. Both CM and MOH show particular genetic background able to favor the appearance of chronicity and abuse. Rehabilitation consists of drug withdrawal procedures, re-prophylaxis through administration of innovative drugs, such as OnabotulinumtoxinA and/or topiramate, to avoid relapsing attacks, and behavioral strategies to minimize the role of risk factors. The initial relief step for drug abusers always relies in drug withdrawal. The feasible diagnostic setting for a CM tailored treatment based on the application of pharmacogenomics will allow us to predetermine the efficacy of single old and new drugs by avoiding abuse due to non-responsivity of the acute drug.

Indexed as

AnalgesicsCardiovascular DiseasesChronic DiseaseComorbidityDisease ProgressionHumansInactivation, MetabolicItalyLife StyleMental DisordersMigraine DisordersPrescription DrugsRisk FactorsSubstance Withdrawal SyndromeTryptaminesAnalgesicsPrescription DrugsTryptamines

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.