Evidence map›Paper›PMID 20865434›Full record

ReviewJournal of neural transmission (Vienna, Austria : 1996)2011

New aspects of the molecular constituents of tissue barriers.

H C Bauer, A Traweger, J Zweimueller-Mayer, C Lehner, H Tempfer, I Krizbai, I Wilhelm, H Bauer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neural transmission (Vienna, Austria : 1996), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Foe or friend? Janus-faces of the neurovascular unit in the formation of brain metastases.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018
    Review
  8. Review
  9. Review
  10. Article
  11. Electroporation-mediated delivery of genes in rodent models of lung contusion.Methods in molecular biology (Clifton, N.J.) · 2014
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Role of the blood-brain barrier in the formation of brain metastases.International journal of molecular sciences · 2013
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

H C BauerDepartment of Organismic Biology, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria.
A Traweger
J Zweimueller-Mayer
C Lehner
H Tempfer
I Krizbai
I Wilhelm
H Bauer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial and endothelial tissue barriers are based on tight intercellular contacts (Tight Junctions, TJs) between neighbouring cells. TJs are multimeric complexes, located at the most apical border of the lateral membrane. So far, a plethora of proteins locating at tight intercellular contacts have been discovered, the role of which has just partly been unraveled. Yet, there is convincing evidence that many TJ proteins exert a dual role: They act as structural components at the junctional site and they are involved in signalling pathways leading to alterations of gene expression and cell behaviour (migration, proliferation). This review will shortly summarize the classical functions of TJs and TJ-related proteins and will introduce a new category, termed the "non-classical" functions of junctional proteins. A particular focus will be directed towards the nuclear targeting of junctional proteins and the downstream effects elicited by their intranuclear activities.

Indexed as

AnimalsCell NucleusEndotheliumEpithelial CellsHumansMembrane ProteinsNerve Tissue ProteinsTight JunctionsMembrane ProteinsNerve Tissue Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.