ArticleAnnals of surgical oncology2011
An elevated body mass index does not reduce survival after esophagectomy for cancer.
Article in Annals of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Impact of high body mass index on surgical outcomes and long-term survival among patients undergoing esophagectomy: A meta-analysis.Medicine · 2018Pooled it
- Positive Effect of Higher Adult Body Mass Index on Overall Survival of Digestive System Cancers Except Pancreatic Cancer: A Systematic Review and Meta-Analysis.BioMed research international · 2017Pooled it
- The impact of body mass index on complication and survival in resected oesophageal cancer: a clinical-based cohort and meta-analysis.British journal of cancer · 2013Pooled it
- Does obesity affect outcomes in patients undergoing esophagectomy for cancer? A meta-analysis.World journal of surgery · 2012Pooled it
- Does high body mass index influence the postoperative complications and long-term survival in patients with esophageal squamous cell carcinoma after minimally invasive esophagectomy?Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Factors Affecting Blood Loss During Thoracoscopic Esophagectomy for Esophageal Carcinoma.Journal of chest surgery · 2021Article
- Visceral Obesity, Metabolic Syndrome, and Esophageal Adenocarcinoma.Frontiers in oncology · 2021Review
- Prediagnostic adult body mass index change and esophageal adenocarcinoma survival.Cancer medicine · 2020Article
- The prognostic influence of body mass index, resting energy expenditure and fasting blood glucose on postoperative patients with esophageal cancer.BMC gastroenterology · 2016Article
- Spirometric Lung Age Predicts Postoperative Pneumonia After Esophagectomy.World journal of surgery · 2016Article
- Prognostic significance of the pN classification supplemented by body mass index for esophageal squamous cell carcinoma.Thoracic cancer · 2015Article
- Impact of body mass index on survival of esophageal squamous carcinoma patients in southern China.Journal of thoracic disease · 2015Article
- Obesity Does Not Influence Outcomes in Hepatocellular Carcinoma Patients following Curative Hepatectomy.PloS one · 2015Article
- Genetic variants of EGF and VEGF predict prognosis of patients with advanced esophageal squamous cell carcinoma.PloS one · 2014Article
- Initial experience from a large referral center with robotic-assisted Ivor Lewis esophagogastrectomy for oncologic purposes.Surgical endoscopy · 2013Article
- Comparison of the prognostic values of various nutritional parameters in patients with esophageal squamous cell carcinoma from Southern China.Journal of thoracic disease · 2013Article
- Defining the learning curve for robotic-assisted esophagogastrectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Article
- Overweight patients operated on for cancer of the esophagus survive longer than normal-weight patients.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013Article
- The effects of Photofrin-mediated photodynamic therapy on the modulation of EGFR in esophageal squamous cell carcinoma cells.Lasers in medical science · 2013Article
- Body mass index and survival in esophageal adenocarcinoma treated with chemoradiotherapy followed by esophagectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundIncidences of esophageal cancer and obesity are both rising in the United States. The aim of this study was to determine the influence of elevated body mass index on outcomes after esophagectomy for cancer.
methodsOverall and disease-free survivals in obese (BMI ≥ 30), overweight (BMI 25-29), and normal-weight (BMI 20-24) patients undergoing esophagectomy constituted the study end points. Survivals were calculated by the Kaplan-Meier method, and differences were analyzed by log rank method.
resultsThe study included 166 obese, 176 overweight, and 148 normal-weight patients. These three groups were similar in terms of demographics and comorbidities, with the exception of younger age (62.5 vs. 66.2 vs. 65.3 years, P = 0.002), and higher incidence of diabetes (23.5 vs. 11.4 vs. 10.1%, P = 0.001) and hiatal hernia (28.3 vs. 14.8 vs. 20.3%, P = 0.01) in obese patients. Rates of adenocarcinoma histology were higher in obese patients (90.8 vs. 90.9 vs. 82.5%, P = 0.03). Despite similar preoperative stage, obese patients were less likely to receive neoadjuvant treatment (47.6 vs. 54.5 vs. 66.2%, P = 0.004). Response to neoadjuvant treatment, type of surgery performed, extent of lymphadenectomy, rate of R0 resections, perioperative complications, and administration of adjuvant chemotherapy were not influenced by BMI. At a median follow-up of 25 months, 5-year overall and disease-free survivals were longer in obese patients (respectively, 48, 41, 34%, P = 0.01 and 48, 44, 34%, P = 0.01).
conclusionsIn our experience, an elevated BMI did not reduce overall and disease-free survivals after esophagectomy for cancer.
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