Evidence map›Paper›PMID 20865079›Full record

ArticleClinical epidemiology2009

Venous and arterial thrombosis: Two aspects of the same disease?

Paolo Prandoni

Abstract read
In one paragraph

Article in Clinical epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Haemostasis and the Need for Antithrombotics: An Introduction.Handbook of experimental pharmacology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Linking Labile Heme with Thrombosis.Journal of clinical medicine · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Thrombogenic and Inflammatory Reactions to Biomaterials in Medical Devices.Frontiers in bioengineering and biotechnology · 2020
    Review
  13. Review
  14. Article
  15. Relation of coagulation factor XI with incident coronary heart disease and stroke: the Cardiovascular Health Study.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis · 2017
    Article
  16. An exploratory look at NETosis in atherosclerosis.Internal and emergency medicine · 2017
    Review
  17. Observational
  18. Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Paolo PrandoniDepartment of Cardiothoracic and Vascular Sciences, Thromboembolism Unit, University Hospital of Padua Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing body of evidence suggests the likelihood of a link between venous and arterial thrombosis. The two vascular complications share several risk factors, such as age, obesity, diabetes mellitus, blood hypertension, hypertriglyceridemia, and metabolic syndrome. Moreover, there are many examples of conditions accounting for both venous and arterial thrombosis, such as the antiphospholipid antibody syndrome, hyperhomocysteinemia, malignancies, infections, and the use of hormonal treatment. Finally, several recent studies have consistently shown that patients with venous thromboembolism are at a higher risk of arterial thrombotic complications than matched control individuals. We, therefore, speculate the two vascular complications are simultaneously triggered by biological stimuli responsible for activating coagulation and inflammatory pathways in both the arterial and the venous system. Future studies are needed to clarify the nature of this association, to assess its extent, and to evaluate its implications for clinical practice.

Indexed as

atherosclerosisdeep vein thrombosisischemic strokemyocardial infarctionpulmonary embolismvenous thromboembolism

Identifiers

PMID20865079
PMCPMC2943163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.