ArticleMolecular systems biology2010
Understanding the physiology of Lactobacillus plantarum at zero growth.
Article in Molecular systems biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Fractional ethanol precipitation modulates the structure and function ofFrontiers in nutrition · 2026Article
- Review
- Unveiling the potential of Loigolactobacillus coryniformis BCH-4 to ameliorate drought stress in Zea mays L.World journal of microbiology & biotechnology · 2025Article
- Lactic acid bacteria: A sustainable solution against phytopathogenic agents.Environmental microbiology reports · 2024Review
- Characterising the metabolic rewiring of extremely slow growing Komagataella phaffii.Microbial biotechnology · 2024Article
- Quantitative Physiology and Proteome Adaptations of Bifidobacterium breve NRBB57 at Near-Zero Growth Rates.Microbiology spectrum · 2023Article
- Article
- The potential of lactic acid bacteria in mediating the control of plant diseases and plant growth stimulation in crop production - A mini review.Frontiers in plant science · 2022Review
- An alternative resource allocation strategy in the chemolithoautotrophic archaeonProceedings of the National Academy of Sciences of the United States of America · 2021Article
- A Wake-Up Call for the Efficient Use of the Bacterial Resting Cell Process, with Focus on Low Solubility Products.Current microbiology · 2020Review
- Drosophila-associated bacteria differentially shape the nutritional requirements of their host during juvenile growth.PLoS biology · 2020Article
- Article
- Extracellular Vesicles Derived fromExperimental neurobiology · 2019Article
- Application of a partial cell recycling chemostat for continuous production of aroma compounds at near-zero growth rates.BMC research notes · 2019Article
- Long-Term Transcriptional Activity at Zero Growth of a Cosmopolitan Rare Biosphere Member.mBio · 2019Article
- Article
- Bacterial Adaptation to the Host's Diet Is a Key Evolutionary Force Shaping Drosophila-Lactobacillus Symbiosis.Cell host & microbe · 2018Article
- Constraint-based modeling in microbial food biotechnology.Biochemical Society transactions · 2018Review
- Systems biology of lactic acid bacteria: For food and thought.Current opinion in systems biology · 2017Review
- Probing the Genome-Scale Metabolic Landscape of Bordetella pertussis, the Causative Agent of Whooping Cough.Applied and environmental microbiology · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Situations of extremely low substrate availability, resulting in slow growth, are common in natural environments. To mimic these conditions, Lactobacillus plantarum was grown in a carbon-limited retentostat with complete biomass retention. The physiology of extremely slow-growing L. plantarum--as studied by genome-scale modeling and transcriptomics--was fundamentally different from that of stationary-phase cells. Stress resistance mechanisms were not massively induced during transition to extremely slow growth. The energy-generating metabolism was remarkably stable and remained largely based on the conversion of glucose to lactate. The combination of metabolic and transcriptomic analyses revealed behaviors involved in interactions with the environment, more particularly with plants: production of plant hormones or precursors thereof, and preparedness for the utilization of plant-derived substrates. Accordingly, the production of compounds interfering with plant root development was demonstrated in slow-growing L. plantarum. Thus, conditions of slow growth and limited substrate availability seem to trigger a plant environment-like response, even in the absence of plant-derived material, suggesting that this might constitute an intrinsic behavior in L. plantarum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.