ArticleNeuro-oncology2010
Increases in the number of brain metastases detected at frame-fixed, thin-slice MRI for gamma knife surgery planning.
Article in Neuro-oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Deep learning-based image enhancement for improved black blood imaging in brain metastasis.European radiology · 2026Article
- Evaluating liquid biopsy biomarkers for early detection of brain metastasis: A systematic review.Neuro-oncology practice · 2025Article
- Impact of MRI resolution for Linac-based stereotactic radiosurgery.Frontiers in oncology · 2023Article
- Influence of COVID-19 pandemic on the decision making of patients in undergoing gamma knife radiosurgery.European journal of medical research · 2022Article
- The Clinical, Diagnostic, Therapeutic, and Prognostic Characteristics of Brain Metastases in Prostate Cancer: A Systematic Review.Prostate cancer · 2022Article
- Discovery of increased number or interval growth of brain metastases on same-day GammaKnife™ planning MRI: Predicting factors and patient outcomes.Journal of radiosurgery and SBRT · 2022Article
- Comparison of radiomic feature aggregation methods for patients with multiple tumors.Scientific reports · 2021Article
- The value of DTI: achieving high diagnostic performance for brain metastasis.La Radiologia medica · 2021Article
- MRI-based radiosurgical planning: implications in imaging timing.Annals of translational medicine · 2019Article
- Pre-treatment factors associated with detecting additional brain metastases at stereotactic radiosurgery.Journal of neuro-oncology · 2016Article
- ACR Appropriateness Criteria® pre-irradiation evaluation and management of brain metastases.Journal of palliative medicine · 2014Review
- The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2014Review
- Treatment of single or multiple brain metastases by hypofractionated stereotactic radiotherapy using helical tomotherapy.International journal of molecular sciences · 2014Article
- Imaging of brain metastases.Surgical neurology international · 2013Article
- Regression curves of brain metastases after gamma knife irradiation: Difference by tumor and patient characteristics.Cancer science · 2012Article
- The Effect of Slice Thickness on Contours of Brain Metastases for Stereotactic Radiosurgery.Advances in radiation oncologyArticle
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
For gamma knife planning, 2.4-mm-slice MRIs are taken under rigid frame fixation, so tiny tumors become visible. This study evaluated differences in the numbers of brain metastases between conventional contrast-enhanced MRI (6 ± 1 mm slice thickness) taken before patient referral and contrast-enhanced MRI for gamma knife planning. The numbers of metastases on the 2 images were counted by at least 2 oncologists. For gamma knife planning, spoiled gradient-recalled echo images were obtained after 0.1 mmol/kg gadolinium administration using a 1.5-T system. Images from 1045 patients with an interval between the 2 MRI studies of 6 weeks or less were analyzed. Increases in the number of metastases were found in 33.7% of the 1045 patients, whereas the number was identical in 62.3%. In 4.0%, the number decreased, indicating overdiagnosis at conventional MRI. These proportions did not differ significantly by the interval before gamma knife. An increase from single to multiple metastases was found in 16.0%. Meningeal dissemination was newly diagnosed in 2.3%. On planning images, the proportions of patients with 1, 2, 3, and 4 or more lesions were 37.6%, 19.3%, 9.3%, and 33.8%, respectively. In cases of colorectal cancer and hepatoma, the proportions of patients with a single metastasis (32 of 61 [52%] and 5 of 6 [83%], respectively) were higher than that of patients with other malignancies. In about one-third of the patients, an increased number of metastases were found on the thin-slice images. This should be kept in mind when deciding the treatment strategy for brain metastases.
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