ArticleObesity surgery2011
Gastric emptying and postprandial PYY response after biliopancreatic diversion with duodenal switch.
Article in Obesity surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- The role of PYY in improving insulin resistance.Frontiers in endocrinology · 2026Review
- Dual-Isotope Scintigraphy for Gastrointestinal Transit in Duodenal Switch: An Explorative Clinical Study.Obesity surgery · 2025Article
- Review
- Marginal Ulcer and Dumping Syndrome in Patients after Duodenal Switch: A Multi-Centered Study.Journal of clinical medicine · 2023Article
- Article
- Gastric Sensory and Motor Functions and Energy Intake in Health and Obesity-Therapeutic Implications.Nutrients · 2021Review
- The Effects of Bariatric Surgery on Islet Function, Insulin Secretion, and Glucose Control.Endocrine reviews · 2019Review
- The Effects of Bariatric Procedures on Bowel Habit.Obesity surgery · 2016Observational
- The effect of bariatric surgery on intestinal absorption and transit time.Obesity surgery · 2014Article
- Evaluation of an In Silico PBPK Post-Bariatric Surgery Model through Simulating Oral Drug Bioavailability of Atorvastatin and Cyclosporine.CPT: pharmacometrics & systems pharmacology · 2013Article
- Dumping syndrome following gastric bypass: validation of the dumping symptom rating scale.Obesity surgery · 2013Article
- The role of hormonal factors in weight loss and recidivism after bariatric surgery.Gastroenterology research and practice · 2013Review
- Bariatric surgery and the central nervous system.Obesity surgery · 2012Review
- Gastric emptying after sleeve gastrectomy.Obesity surgery · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuper-obesity (BMI > 50) is increasing rapidly. We use the biliopancreatic diversion with duodenal switch (BPD-DS) as one option in this patient category. The aim of the present study was to investigate the emptying of the gastric tube, PYY levels and dumping symptoms after BPD-DS.
methodsEmptying of the gastric tube was investigated with scintigraphy after an overnight fast. Twenty patients (median age 43 years, BMI 31.1 kg/m²) having undergone BPD-DS in median 3.5 years previously were included in the scintigraphic study. A technetium-labelled omelette was ingested and scintigraphic evaluation of gastric emptying was undertaken. Ten of the patients also underwent PYY measurements after a standardised meal and were compared to nine non-operated age-matched normal weight controls, both in the fasting state and after the test meal. Frequency of dumping symptoms was evaluated in all patients.
resultsThe half-emptying time was 28 ± 16 min. Lag phase was present in 30% of the patients. PYY levels were significantly higher in BPD-DS patients as compared to controls both in the fasting state (p < 0.001) and after the test meal (p < 0.001). Dumping symptoms were scarce and occurred in 17 of the 20 patients only few times yearly or less.
conclusionsAlthough the pylorus is preserved in BPD-DS, the stomach emptying is faster than in non-operated subjects. PYY levels are elevated in the fasting state after BPD-DS and a marked response to a test meal is seen, likely due to the rapid stimulation of intraluminal nutrients in the distal ileum. In spite of this, dumping symptoms are uncommon.
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