ArticleInternational journal of pediatrics2010
Developmental Changes in Hemodynamic Responses and Cardiovagal Modulation during Isometric Handgrip Exercise.
Article in International journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Acute Blood Pressure Response to Different Types of Isometric Exercise: A Systematic Review with Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Heart rate variability changes in adolescents following surgical correction of aortic coarctation: Persistent autonomic alterations.Physiological reports · 2026Article
- Fetal and Infant Growth and the Cardiovascular Stress Response in Adolescence: A Cardiovascular Magnetic Resonance Imaging Study in a Pediatric Population-Based Cohort.Journal of the American Heart Association · 2025Article
- Physical exercise and cardiovascular response: design and implementation of a pediatric CMR cohort study.The international journal of cardiovascular imaging · 2023Article
- The Cardiovascular Stress Response as Early Life Marker of Cardiovascular Health: Applications in Population-Based Pediatric Studies-A Narrative Review.Pediatric cardiology · 2020Review
- Determinants of muscle metaboreflex and involvement of baroreflex in boys and young men.European journal of applied physiology · 2013Article
- Blood Pressure Control at Rest and during Exercise in Obese Children and Adults.Journal of obesity · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to examine differences in pressor response and cardiovagal modulation during isometric handgrip exercise (IHG) between children and adults. Beat-to-beat heart rate (HR) and blood pressure were measured in 23 prepubertal children and 23 adults at baseline and during IHG. Cardiovagal modulation was quantified by analysis of HR variability. Mean arterial pressure responses to IHG were greater in adults compared to children (P < .05) whereas there were no group differences in HR responses (P > .05). Children had a greater reduction in cardiovagal modulation in response to IHG compared to adults (P < .05). Changes in mean arterial pressure during IHG were correlated with baseline cardiovagal modulation and force produced during isometric contraction (P < .05). In conclusion, differences in pressor reflex response between children and adults cannot be solely explained by differences in autonomic modulation and appear to be associated with factors contributing to the force produced during isometric contraction.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.