Evidence map›Paper›PMID 20861879›Full record

ReviewNature reviews. Molecular cell biology2010

Revitalizing membrane rafts: new tools and insights.

Kai Simons, Mathias J Gerl

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 566 papers.

0numbers the graph read from it
0cells of the map it votes in
566citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

566 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Metabolic Control of Membrane Lipid Asymmetry in Cancer.International journal of molecular sciences · 2026
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Hydration gradients drive lipid self-segregation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  17. Review
  18. Review
  19. Review
  20. Article

506 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kai SimonsMax Planck Institute of Cell Biology and Genetics, Dresden, Germany. simons@mpi-cbg.de
Mathias J Gerl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ten years ago, we wrote a Review on lipid rafts and signalling in the launch issue of Nature Reviews Molecular Cell Biology. At the time, this field was suffering from ambiguous methodology and imprecise nomenclature. Now, new techniques are deepening our insight into the dynamics of membrane organization. Here, we discuss how the field has matured and present an evolving model in which membranes are occupied by fluctuating nanoscale assemblies of sphingolipids, cholesterol and proteins that can be stabilized into platforms that are important in signalling, viral infection and membrane trafficking.

Indexed as

BiophysicsCaveolaeCell MembraneDetergentsHumansMajor Histocompatibility ComplexMass SpectrometryMembrane MicrodomainsSignal TransductionSolubilitySpectrometry, FluorescenceT-LymphocytesDetergents

Identifiers

PMID20861879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.