ArticleScience translational medicine2010
Comment on "The origins of sexually transmitted HIV among men who have sex with men".
Article in Science translational medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Article
- The HIV-1 transmission bottleneck.Retrovirology · 2017Article
- Bottlenecks in HIV-1 transmission: insights from the study of founder viruses.Nature reviews. Microbiology · 2015Review
- Origin of the transmitted virus in HIV infection: infected cells versus cell-free virus.The Journal of infectious diseases · 2014Review
- T cell virological synapses and HIV-1 pathogenesis.Immunologic research · 2012Review
- Response to Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men"Science translational medicine · 2010Article
Corrections and comments
- Comment on
Authors and funding
4 authors.
Funding
Abstract
Whether HIV from seminal cells or free HIV in semen is the origin of transmitted virus has important implications for the design of transmission prevention strategies. We found that a recent claim that HIV originates from seminal plasma and not from seminal cells was erroneous, because it was based on biological specimens that had been mislabeled, mixed-up, or contaminated. The origin of transmitted virus from semen therefore remains an open question.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.