Evidence map›Paper›PMID 20861158›Full record

ReviewCold Spring Harbor perspectives in biology2010

In vivo imaging in cancer.

John Condeelis, Ralph Weissleder

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Nanomedicine Innovations for Lung Cancer Diagnosis and Therapy.ACS applied materials & interfaces · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. OptimizediScience · 2024
    Article
  9. Imaging Approaches in Cancer Biology.Cold Spring Harbor perspectives in medicine · 2024
    Review
  10. Article
  11. Motion Blur Microscopy.bioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Mechanobiology in oncology: basic concepts and clinical prospects.Frontiers in cell and developmental biology · 2023
    Review

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John CondeelisAnatomy and Structural Biology, Gruss Lipper Biophotonics Center, Program in Microenvironment and Metastasis, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA. condeeli@aecom.yu.edu
Ralph Weissleder

Funding

Tumor Progression and MetastasisP01CA100324 · NCI · YESHIVA UNIVERSITY · PI CONDEELIS, JOHN S · 2003 to 2018
$30.0M
StatisticsP50CA086355 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2015
$27.8M
TREATMENT OF CANCER WITH siRNA DELVIERED BY NANOPARTICLESU54CA119349 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL · 2005 to 2009
$20.5M
Tumor-Stroma Interacions in the Tumor MicroenvironmentU54CA126515 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HYNES, RICHARD O · 2006 to 2010
$6.5M
Small Animal Imaging Resource GrantR24CA092782 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, RALPH · 2001 to 2006
$4.2M
Magnetic nanoswitches for sensing biomoleculesR01EB004626 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2004 to 2012
$3.2M
Small Animal Imaging ResourceU24CA092782 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS, WEISSLEDER, MD, PHD, RALPH · 2007 to 2011
$2.7M
Novel Methods for Detecting Cell Interactions in the Tumor MicroenvironmentU54CA126511 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S · 2006 to 2010
$2.2M
MICROENVIRONMENTS OF INVASION IN HUMAN BREAST TUMORSR01CA113395 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S · 2006 to 2010
$1.4M
NCI NIH HHS CA100324NCI NIH HHS CA113395NCI NIH HHS CA119394NCI NIH HHS CA126511NCI NIH HHS CA126515NCI NIH HHS CA86355NCI NIH HHS CA92782NCI NIH HHS P01 CA100324NCI NIH HHS P50 CA086355NCI NIH HHS R01 CA113395NCI NIH HHS R24 CA092782NCI NIH HHS U24 CA092782NCI NIH HHS U54 CA119349NCI NIH HHS U54 CA126511NCI NIH HHS U54 CA126515NIBIB NIH HHS EB004626NIBIB NIH HHS R01 EB004626
6 · The paper itself

Abstract

Imaging has become an indispensable tool in the study of cancer biology and in clinical prognosis and treatment. The rapid advances in high resolution fluorescent imaging at single cell level and MR/PET/CT image registration, combined with new molecular probes of cell types and metabolic states, will allow the physical scales imaged by each to be bridged. This holds the promise of translation of basic science insights at the single cell level to clinical application. In this article, we describe the recent advances in imaging at the macro- and micro-scale and how these advances are synergistic with new imaging agents, reporters, and labeling schemes. Examples of new insights derived from the different scales of imaging and relevant probes are discussed in the context of cancer progression and metastasis.

Indexed as

Diagnostic ImagingHumansNeoplasm MetastasisNeoplasmsStaining and Labeling

Identifiers

PMID20861158
PMCPMC2982169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.