Evidence map›Paper›PMID 20860799›Full record

ArticleBMC genomics2010

The first-generation Daphnia magna linkage map.

Jarkko Routtu, Bastiaan Jansen, Isabelle Colson, Luc De Meester, Dieter Ebert

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Genome Assembly of a Relict Arabian Species ofInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Identification of Mitochondrial DNA (NUMTs) in the Nuclear Genome ofInternational journal of molecular sciences · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Jarkko RouttuZoologisches Institut, Evolutionsbiologie, Universität Basel, Vesalgasse 1, 4051 Basel, Switzerland. jarkko.routtu@unibas.ch
Bastiaan Jansen
Isabelle Colson
Luc De Meester
Dieter Ebert
KU Leuven · BEUniversity of Basel · CHBangor University · GB

Funding

Daphnia Functional Genomics ResourceR24GM078274 · NIGMS · UTAH STATE UNIVERSITY · PI PFRENDER, MICHAEL EUGENE · 2007 to 2010
$1.4M
NIGMS NIH HHS 5R24GM078274
6 · The paper itself

Abstract

backgroundDaphnia magna is a well-established model species in ecotoxicology, ecology and evolution. Several new genomics tools are presently under development for this species; among them, a linkage map is a first requirement for estimating the genetic background of phenotypic traits in quantitative trait loci (QTL) studies and is also very useful in assembling the genome. It also enables comparative studies between D. magna and D. pulex, for which a linkage map already exists.

resultsHere we describe the first genetic linkage map of D. magna. We generated 214 F2 (intercross) clonal lines as the foundation of the linkage analysis. The linkage map itself is based on 109 microsatellite markers, which produced ten major linkage groups ranging in size from 31.1 cM to 288.5 cM. The total size of this linkage map extends to 1211.6 Kosambi cM, and the average interval for the markers within linkage groups is 15.1 cM. The F2 clones can be used to map QTLs for traits that differ between the parental clones. We successfully mapped the location of two loci with infertility alleles, one inherited from the paternal clone (Iinb1) and the other from the maternal clone (Xinb3).

conclusionsThe D. magna linkage map presented here provides extensive coverage of the genome and a given density of markers that enable us to detect QTLs of moderate to strong effects. It is similar in size to the linkage map of D. pulex.

Indexed as

Chromosome MappingAllelesAnimalsDaphniaExpressed Sequence TagsFemaleGenetic LociGenetic MarkersGenotypeInfertilityLinkage DisequilibriumLod ScoreMaleMinisatellite RepeatsGenetic Markers

Identifiers

PMID20860799
PMCPMC2997004
OpenAlexW2136575611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.