Evidence map›Paper›PMID 20860481›Full record

ReviewFuture microbiology2010

Immune evasion by Kaposi's sarcoma-associated herpesvirus.

Hye-Ra Lee, Stacy Lee, Preet M Chaudhary, Parkash Gill, Jae U Jung

Open access · greenAbstract readReview
In one paragraph

Review in Future microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 59 citations in OpenAlex.

  1. Macrophages in oncoviral infections: from immune regulators to therapeutic targets.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Insight into the Epigenetics of Kaposi's Sarcoma-Associated Herpesvirus.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
  10. Kaposi Sarcoma, a Trifecta of Pathogenic Mechanisms.Diagnostics (Basel, Switzerland) · 2022
    Review
  11. G-Quadruplex Targeting in the Fight against Viruses: An Update.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hye-Ra LeeDepartment of Molecular Microbiology & Immunology, University of Southern California, Los Angeles, CA 90033, USA. hyelee@usc.edu
Stacy Lee
Preet M Chaudhary
Parkash Gill
Jae U Jung
University of Southern California · US

Funding

TRIM mediated host antiviral responses during influenza virus infectionsU19AI083025 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2009 to 2013
$10.0M
ORF36 Viral Kinase as a Transcriptional Regulator of KSHVP01DE019085 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUN, REN · 2008 to 2012
$6.4M
Molecular Basis of KSHV PathogenesisR01CA082057 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 1999 to 2016
$5.1M
MOLECULAR BASIS FOR HERPESVIRUS SAIMIRI ONCOGENICITYR01CA031363 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 1985 to 2014
$4.9M
Role of viral BCI-2 mediated anti-apoptosis and-autophagyR01AI073099 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2007 to 2017
$4.3M
KSHV RTA: more than viral replicationR01CA115284 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2005 to 2015
$3.1M
Live-attenuated KSHV as vaccine candidateRC2CA148616 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2009 to 2010
$1.0M
Peptide-mediated immunotherapy of KSHV-associated malignancy.RC1CA147868 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JUNG, JAE U · 2009 to 2010
$993k
NCI NIH HHS CA082057NCI NIH HHS CA115284NCI NIH HHS CA147868NCI NIH HHS CA148616NCI NIH HHS CA31363NCI NIH HHS R01 CA031363NCI NIH HHS R01 CA082057NCI NIH HHS R01 CA115284NCI NIH HHS RC1 CA147868NCI NIH HHS RC2 CA148616NIAID NIH HHS AI073099NIAID NIH HHS AI083025NIAID NIH HHS R01 AI073099NIAID NIH HHS U19 AI083025NIDCR NIH HHS DE019085NIDCR NIH HHS P01 DE019085
6 · The paper itself

Abstract

Persistent viral infections are often associated with serious diseases, primarily by altering functions of the host immune system. The hallmark of Kaposi's sarcoma-associated herpesvirus (KSHV) infection is the establishment of a life-long persistent infection, which leads to several clinical, epidemiological and infectious diseases, such as Kaposi's sarcoma, a plasmablastic variant of multicentric Castleman's disease, and primary effusion lymphoma. To sustain an efficient life-long persistency, KSHV dedicates a large portion of its genome to encoding immunomodulatory proteins that antagonize the immune system of its host. In this article, we highlight the strategies KSHV uses to evade, escape and survive its battle against the host's immune system.

Indexed as

Immune EvasionAnimalsHerpesvirus 8, HumanHumansLymphoma, Primary EffusionMiceSarcoma, Kaposi

Identifiers

PMID20860481
PMCPMC3076960
OpenAlexW2059108822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.