ArticleEuropean journal of clinical nutrition2011
Determinants of plasma alkylresorcinol concentration in Danish post-menopausal women.
Article in European journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biomarkers of Whole-Grain and Cereal-Fiber Intake in Human Studies: A Systematic Review of the Available Evidence and Perspectives.Nutrients · 2019Pooled it
- Comparison of plasma alkylresorcinols (AR) and urinary AR metabolites as biomarkers of compliance in a short-term, whole-grain intervention study.European journal of nutrition · 2016Trial
- Plasma alkylresorcinols, biomarkers of whole-grain intake, are not associated with progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease.Public health nutrition · 2016Trial
- Alkylresorcinols in adipose tissue biopsies as biomarkers of whole-grain intake: an exploratory study of responsiveness to advised intake over 12 weeks.European journal of clinical nutrition · 2015Trial
- Plasma alkylresorcinols as a biomarker of whole-grain food consumption in a large population: results from the WHOLEheart Intervention Study.The American journal of clinical nutrition · 2012Trial
- Alkylresorcinol, a biomarker for whole grain intake, and its association with osteoarthritis: the MOST study.Osteoarthritis and cartilage · 2022Article
- Use of a Web-Based Dietary Assessment Tool (RiksmatenFlex) in Swedish Adolescents: Comparison and Validation Study.Journal of medical Internet research · 2019Article
- Biomarkers of cereal food intake.Genes & nutrition · 2019Review
- New alkylresorcinol metabolites in spot urine as biomarkers of whole grain wheat and rye intake in a Swedish middle-aged population.European journal of clinical nutrition · 2018Article
- Urinary excretions of 34 dietary polyphenols and their associations with lifestyle factors in the EPIC cohort study.Scientific reports · 2016Article
- Validity of a web-based dietary questionnaire designed especially to measure the intake of phyto-oestrogens.Journal of nutritional science · 2016Article
- Plasma alkylresorcinols, biomarkers of whole-grain wheat and rye intake, and incidence of colorectal cancer.Journal of the National Cancer Institute · 2014Article
- Long-term reproducibility of plasma alkylresorcinols as biomarkers of whole-grain wheat and rye intake within Northern Sweden Health and Disease Study Cohort.European journal of clinical nutrition · 2013Article
- Plasma alkylresorcinols, biomarkers of whole-grain intake, are related to lower BMI in older adults.The Journal of nutrition · 2012Article
- Alkylresorcinol metabolite concentrations in spot urine samples correlated with whole grain and cereal fiber intake but showed low to modest reproducibility over one to three years in U.S. women.The Journal of nutrition · 2012Article
- Present status and perspectives on the use of alkylresorcinols as biomarkers of wholegrain wheat and rye intake.Journal of nutrition and metabolism · 2012Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlkylresorcinols (AR), a group of phenolic lipids present in the outer parts of wheat and rye grain kernels, have been suggested as biomarkers of whole-grain wheat and rye intake. In this study, we investigated potential determinants of plasma AR concentration in a free-living population. SUBJECTS/
methodsNon-fasting samples from post-menopausal women enrolled in the Danish Diet, Cancer and Health study (n = 360) were selected. Diet was assessed using a semi-quantitative food frequency questionnaires (FFQ) and the association between food items likely to contain AR and relevant non-dietary factors were studied by analysis of covariance models.
resultsThe median AR concentration was 78 nmol/l (interquartile range = 106.9 nmol/l). Intake of rye bread, identified as the main determinant, was associated with 87% higher plasma total AR concentration per 100 g of bread (95% confidence interval = 46-139%). About 8-12% of the total variation (depending on the AR homologue) in plasma AR concentration was explained by the selected dietary variables. At a nutrient level, total dietary fiber and cereal fiber were significantly associated with plasma total AR concentration (P = 0.05), but only ≈2% of the total plasma AR concentration was explained by the dietary fiber or cereal fiber intake.
conclusionsIn the studied population, AR plasma concentration was mainly affected by rye bread intake among investigated determinants.
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