Trial reportChemical senses2010
Dynamics of nasal irritation from pulsed homologous alcohols.
Trial report in Chemical senses, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Relatively, few studies have focused on how nasal irritation changes over time. To simulate the rhythm of natural respiration, subjects received 3-s pulses of volatile organic compounds interspersed with 3-s pulses of clean air. Each trial, subjects received 9 pulses of a chemical vapor over about 1 min. Subjects rated nasal irritation from each pulse using magnitude estimation. Within a trial, compound and concentration were fixed. Compound (ethanol, n-butanol, or n-hexanol) and concentration (4 levels for each compound) varied across trials. For all stimuli, rated irritation decreased over time (adaptation). Plots of log-rated intensity versus elapsed time were approximately linear (intensity decreased by a fixed ratio per unit time). Interestingly, the slopes of intensity versus time functions differed very little: Regardless of concentration and compound, rated irritation decreased by about 32% over the 9 pulses. The basic mechanism of short-term adaptation may be the same for the 3 alcohols studied. Regardless, these data suggest that very simple models might be able to describe some aspects of perceptual dynamics quite well.
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Registered trials
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