Evidence map›Paper›PMID 20858366›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2010

Treatment and eradication of murine fur mites: III. Treatment of a large mouse colony with ivermectin-compounded feed.

Rodolfo J Ricart Arbona, Neil S Lipman, Felix R Wolf

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Safety and efficacy of topical lime sulfur in mice infested with Myocoptes musculinus.Journal of the American Association for Laboratory Animal Science : JAALAS · 2013
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ivermectin-compounded Feed Compared with Topical Moxidectin-Imidacloprid for Eradication ofJournal of the American Association for Laboratory Animal Science : JAALAS · 2018
    Article
  8. Characterization ofComparative medicine · 2017
    Article
  9. Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected withJournal of the American Association for Laboratory Animal Science : JAALAS · 2017
    Article
  10. Total IgE as a serodiagnostic marker to aid murine fur mite detection.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012
    Article
  11. Comparison of a fur mite PCR assay and the tape test for initial and posttreatment diagnosis during a natural infection.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012
    Article
  12. Infectious disease survey of Mus musculus from pet stores in New York City.Journal of the American Association for Laboratory Animal Science : JAALAS · 2012
    Article
  13. Effect of sampling strategy on the detection of fur mites within a naturally infested colony of mice (Mus musculus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2011
    Article
  14. Treatment and eradication of murine fur mites: I. Toxicologic evaluation of ivermectin-compounded feed.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010
    Article
  15. Treatment and eradication of murine fur mites: II. Diagnostic considerations.Journal of the American Association for Laboratory Animal Science : JAALAS · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rodolfo J Ricart ArbonaTri-Institutional Training Program in Laboratory Animal Medicine and Science, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College and The Rockefeller University, New York, New York, USA. ricartr@pi.cpmc.columbia.edu
Neil S Lipman
Felix R Wolf

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

We determined the efficacy of ivermectin-compounded feed against fur mites in mice and describe its use to eradicate mites in vivaria holding approximately 30,000 cages. C57BL/6NCrl mice infested with Myobia musculi and Myocoptes musculinus were treated with ivermectin-compounded feed (approximate ingested dose, 1.3 mg/kg) for 1, 4, or 8 consecutive weeks. Regardless of treatment duration, all treated mice, as well as contact sentinels, remained free of fur mites for as long as 21 wk after treatment. No adverse effects were observed. Subsequently, facility-wide treatment was implemented in an attempt to eradicate fur mites from 3 vivaria housing approximately 120,000 mice. Medicated feed was provided for 8 wk to ensure that all cages and mice were treated. A single investigative group reported adverse effects in their colony 4 wk after treatment was initiated; mortality was attributed to ivermectin toxicity after an intracranial injection at 1 d of age. Naïve pups were unaffected. No other adverse effects were noted. Approximately 14,500 skin scrape samples were evaluated during the 12-mo posttreatment surveillance period. All samples were negative for mites. To our knowledge, this is the first report of successful eradication of fur mites from a mouse colony of this large size.

Indexed as

AcaricidesAnimalsFemaleHairIvermectinMaleMiceMice, Inbred C57BLMice, Inbred StrainsMite InfestationsRodent DiseasesTreatment OutcomeAcaricidesIvermectin

Identifiers

PMID20858366
PMCPMC2949434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.