Evidence map›Paper›PMID 20858269›Full record

ReviewMolecular cancer2010

MicroRNA roles in beta-catenin pathway.

Kai Huang, Jun-Xia Zhang, Lei Han, Yong-Ping You, Tao Jiang, Pei-Yu Pu, Chun-Sheng Kang

Open access · goldAbstract readReview
In one paragraph

Review in Molecular cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 113 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Common miRNAs of Osteoporosis and Fibromyalgia: A Review.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. LncRNA & Wnt signaling in colorectal cancer.Cancer cell international · 2020
    Review
  17. Article
  18. Article
  19. Phytochemical Modulation of MiRNAs in Colorectal Cancer.Medicines (Basel, Switzerland) · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kai HuangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin 300052, China.
Jun-Xia Zhang
Lei Han
Yong-Ping You
Tao Jiang
Pei-Yu Pu
Chun-Sheng Kang
Tianjin Medical University General Hospital · CNCapital Medical University · CNJiangsu Province Hospital · CNNanjing Medical University · CNTianjin Municipal Education Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-catenin, a key factor in the Wnt signaling pathway, has essential functions in the regulation of cell growth and differentiation. Aberrant β-catenin signaling has been linked to various disease pathologies, including an important role in tumorigenesis. Here, we review the regulation of the Wnt signaling pathway as it relates to β-catenin signaling in tumorigenesis, with particular focus on the role of microRNAs. Finally, we discuss the potential of β-catenin targeted therapeutics for cancer treatment.

Indexed as

Animalsbeta CateninHumansMicroRNAsModels, BiologicalNeoplasmsSignal TransductionWnt Proteinsbeta CateninMicroRNAsWnt Proteins

Identifiers

PMID20858269
PMCPMC2955614
OpenAlexW2155011699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.